Wettability modification and the subsequent manipulation of protein adsorption on a Ti6Al4V alloy by means of CO2 laser surface treatment

L. Hao, J. Lawrence

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

Improvements in the wettability of the Ti6Al4V alloy following CO 2 laser treatment were identified as being due mainly to the increase in surface roughness, surface oxygen content and surface energy of the material. Untreated and mechanically roughened samples had higher amounts of adsorbed albumin and lower amounts of adsorbed fibronectin than CO2 laser treated samples. Moreover, as the wettability of the Ti6Al4V alloy increased the adsorbed amounts of fibronectin increased, while the adsorbed amounts of albumin decreased-indicating the controllability of the CO 2 laser process. From this finding it is possible to assert that the wettability of the Ti6Al4V alloy was the prime influence on the observed changes in in vitro protein adsorption. Further, the noted considerable change in the polar component of surface energy, γsvp, on the protein adsorption implied that the protein adsorption on the Ti6Al4V alloy was probably due to the polar and chemical interactions. This work has demonstrated that CO2 laser radiation could be a suitable means to modify the wettability of the Ti6Al4V alloy and thereby manipulate protein adsorption and consequently render the material more bone cell responsive.

Original languageEnglish
Pages (from-to)807-817
Number of pages11
JournalJournal of Materials Science: Materials in Medicine
Volume18
Issue number5
Early online date14 Dec 2006
DOIs
Publication statusPublished - 1 May 2007
Externally publishedYes

Keywords

  • Wettability
  • Simulated Body Fluid
  • Protein Adsorption
  • Ti6Al4V Alloy
  • High Power Diode Laser

ASJC Scopus subject areas

  • Biophysics
  • Bioengineering
  • Biomaterials
  • Biomedical Engineering

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