Validation of Computational Simulation for Tumor-treating Fields with Homogeneous Phantom

Mingwei Ma, Guihang Fu, Minmin Wang, Haipeng Liu, Dingchang Zheng, Yun Pan, Shaomin Zhang

    Research output: Chapter in Book/Report/Conference proceedingConference proceedingpeer-review

    1 Citation (Scopus)
    106 Downloads (Pure)

    Abstract

    Tumor-treating Fields (TTFields) is a promising cancer therapy technique in clinical application. Computational simulation of TTFields has been used to predict the electric field (EF) distribution in the human body and to optimize the treatment parameters. However, there are only a few studies to validate the accuracy of the simulation model. Here we propose a measurement platform with technical details for validating the simulation model of TTFields. We further constructed homogeneous agar phantoms with different conductivity for voltage measurement. With the measured voltages from six equidistance recording points in the cylinder phantom, we calculated the EF intensity in the phantoms at different frequencies. Comparing the measured values with the simulated values obtained from two types of source simulation, we found that the current source simulation model of TTFields is a reliable method for evaluating the EF intensity distribution.

    Original languageEnglish
    Title of host publication2022 44th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)
    PublisherIEEE
    Pages975-978
    Number of pages4
    Volume2022
    ISBN (Electronic)978-1-7281-2782-8
    ISBN (Print)978-1-7281-2783-5
    DOIs
    Publication statusPublished - 8 Sept 2022
    Event44th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. - Glasgow, United Kingdom
    Duration: 11 Jul 202215 Jul 2022

    Publication series

    NameAnnual International Conference of the IEEE Engineering in Medicine and Biology Society.
    PublisherIEEE
    Volume2022
    ISSN (Print)2375-7477
    ISSN (Electronic)2694-0604

    Conference

    Conference44th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.
    Country/TerritoryUnited Kingdom
    CityGlasgow
    Period11/07/2215/07/22

    Bibliographical note

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    Keywords

    • Agar
    • Computer Simulation
    • Electricity
    • Humans
    • Neoplasms/therapy
    • Phantoms, Imaging

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