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Transcription Factors as a Target for Vaccination Against Ticks and Mites

  • Olivier A. E. Sparagano

    Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

    Abstract

    Ticks and mites are well-known ectoparasites as potential vectors for numerous bacteria, viruses, and parasites. Many being blood feeders add to physiological deterioration, morbidity, and mortality of their vertebrate hosts. To control them, transcription factors have been identified and studied in their role to sustain such arthropod pests. This paper summarizes some of the work done on those factors involved during blood feeding, reproduction, or when interacting with their pathogens and symbiont populations. Any transcription factor supporting the equilibrium developed by the ticks/mites could become a potential target for new control methods to prevent some of their key physiological functions.

    Original languageEnglish
    Title of host publicationAdvances in Protein Chemistry and Structural Biology
    EditorsChristo Z. Christov
    PublisherElsevier
    Pages275-282
    Number of pages8
    Volume107
    ISBN (Print)978-0-12-804825-2
    DOIs
    Publication statusPublished - 2017

    UN SDGs

    This output contributes to the following UN Sustainable Development Goals (SDGs)

    1. SDG 3 - Good Health and Well-being
      SDG 3 Good Health and Well-being

    Keywords

    • Mites
    • Ticks
    • Antigen targets
    • Vaccine development
    • Transcription factors

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