The Population Pharmacokinetics of R and S-Warfarin: Effect of Genetic and Clinical Factors

Steven Lane; Sameh Al-Zubiedi; Ellen Hatch; Ivan Matthews; Andrea L. Jorgensen; Panos Deloukas; Ann K. Daly; B. Kevin Park; Leon Aarons; Kayode Ogungbenro; Farhad Kamali; Dyfrig Hughes; Munir Pirmohamed

doi:10.1111/j.1365-2125.2011.04051.x

The Population Pharmacokinetics of R and S-Warfarin: Effect of Genetic and Clinical Factors

Steven Lane, Sameh Al-Zubiedi, Ellen Hatch, Ivan Matthews, Andrea L. Jorgensen, Panos Deloukas, Ann K. Daly, B. Kevin Park, Leon Aarons, Kayode Ogungbenro, Farhad Kamali, Dyfrig Hughes, Munir Pirmohamed

Research output: Contribution to journal › Article

75 Citations (Scopus)

Original language	English
Pages (from-to)	66-76
Journal	British Journal of Clinical Pharmacology
Volume	73
Issue number	1
DOIs	https://doi.org/10.1111/j.1365-2125.2011.04051.x
Publication status	Published - Jan 2012

Keywords

NONMEM software
pharmacogenetics
population pharmacokinetics
warfarin

Access to Document

10.1111/j.1365-2125.2011.04051.x

Cite this

Lane, S., Al-Zubiedi, S., Hatch, E., Matthews, I., Jorgensen, A. L., Deloukas, P., Daly, A. K., Park, B. K., Aarons, L., Ogungbenro, K., Kamali, F., Hughes, D., & Pirmohamed, M. (2012). The Population Pharmacokinetics of R and S-Warfarin: Effect of Genetic and Clinical Factors. British Journal of Clinical Pharmacology, 73(1), 66-76. https://doi.org/10.1111/j.1365-2125.2011.04051.x

Lane, S, Al-Zubiedi, S, Hatch, E, Matthews, I, Jorgensen, AL, Deloukas, P, Daly, AK, Park, BK, Aarons, L, Ogungbenro, K, Kamali, F, Hughes, D & Pirmohamed, M 2012, 'The Population Pharmacokinetics of R and S-Warfarin: Effect of Genetic and Clinical Factors', British Journal of Clinical Pharmacology, vol. 73, no. 1, pp. 66-76. https://doi.org/10.1111/j.1365-2125.2011.04051.x

@article{b5254366913c4631885f75ef57bc07cb,

title = "The Population Pharmacokinetics of R and S-Warfarin: Effect of Genetic and Clinical Factors",

keywords = "NONMEM software, pharmacogenetics, population pharmacokinetics, warfarin",

author = "Steven Lane and Sameh Al-Zubiedi and Ellen Hatch and Ivan Matthews and Jorgensen, {Andrea L.} and Panos Deloukas and Daly, {Ann K.} and Park, {B. Kevin} and Leon Aarons and Kayode Ogungbenro and Farhad Kamali and Dyfrig Hughes and Munir Pirmohamed",

year = "2012",

month = jan,

doi = "10.1111/j.1365-2125.2011.04051.x",

language = "English",

volume = "73",

pages = "66--76",

journal = "British Journal of Clinical Pharmacology",

issn = "1365-2125",

publisher = "Wiley",

number = "1",

}

TY - JOUR

T1 - The Population Pharmacokinetics of R and S-Warfarin: Effect of Genetic and Clinical Factors

AU - Lane, Steven

AU - Al-Zubiedi, Sameh

AU - Hatch, Ellen

AU - Matthews, Ivan

AU - Jorgensen, Andrea L.

AU - Deloukas, Panos

AU - Daly, Ann K.

AU - Park, B. Kevin

AU - Aarons, Leon

AU - Ogungbenro, Kayode

AU - Kamali, Farhad

AU - Hughes, Dyfrig

AU - Pirmohamed, Munir

PY - 2012/1

Y1 - 2012/1

KW - NONMEM software

KW - pharmacogenetics

KW - population pharmacokinetics

KW - warfarin

U2 - 10.1111/j.1365-2125.2011.04051.x

DO - 10.1111/j.1365-2125.2011.04051.x

M3 - Article

SN - 1365-2125

VL - 73

SP - 66

EP - 76

JO - British Journal of Clinical Pharmacology

JF - British Journal of Clinical Pharmacology

IS - 1

ER -