The metabolomic quest for a biomarker in chronic kidney disease

Robert Davies

Research output: Contribution to journalLiterature reviewpeer-review

35 Citations (Scopus)
53 Downloads (Pure)


Chronic kidney disease (CKD) is a growing burden on people and on healthcare for which the diagnostics are neither disease-specific nor indicative of progression. Biomarkers are sought to enable clinicians to offer more appropriate patient-centred treatments, which could come to fruition by using a metabolomics approach. This mini-review highlights the current literature of metabolomics and CKD, and suggests additional factors that need to be considered in this quest for a biomarker, namely the diet and the gut microbiome, for more meaningful advances to be made.
Original languageEnglish
Pages (from-to)694-703
Number of pages11
JournalClinical Kidney Journal
Issue number5
Early online date2 Jun 2018
Publication statusPublished - Oct 2018
Externally publishedYes

Bibliographical note

© The Author(s) 2018. Published by Oxford University Press on behalf of ERA-EDTA.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (, which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact


  • Metabolomics
  • Biomarkers
  • Diet
  • Chronic kidney disease

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Health Professions(all)


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