Abstract
Chronic kidney disease (CKD) is a growing burden on people and on healthcare for which the diagnostics are neither disease-specific nor indicative of progression. Biomarkers are sought to enable clinicians to offer more appropriate patient-centred treatments, which could come to fruition by using a metabolomics approach. This mini-review highlights the current literature of metabolomics and CKD, and suggests additional factors that need to be considered in this quest for a biomarker, namely the diet and the gut microbiome, for more meaningful advances to be made.
Original language | English |
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Pages (from-to) | 694-703 |
Number of pages | 11 |
Journal | Clinical Kidney Journal |
Volume | 11 |
Issue number | 5 |
Early online date | 2 Jun 2018 |
DOIs | |
Publication status | Published - Oct 2018 |
Externally published | Yes |
Bibliographical note
© The Author(s) 2018. Published by Oxford University Press on behalf of ERA-EDTA.This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact [email protected]
Keywords
- Metabolomics
- Biomarkers
- Diet
- Chronic kidney disease
ASJC Scopus subject areas
- Medicine(all)
- Biochemistry, Genetics and Molecular Biology(all)
- Health Professions(all)