The Influence of Polycystic Ovary Syndrome (PCOS) and Other Related Factors upon Health-Related Quality of Life in Women of Reproductive Age: A Case-Control Study

Chris Kite, Ian M. Lahart, Harpal S. Randeva, Ioannis Kyrou, James E. P. Brown

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Abstract

This study aimed to assess the impact of a polycystic ovary syndrome (PCOS) diagnosis and other factors on health-related quality of life (HRQoL) in women of reproductive age. Online questionnaires were completed and study groups compared. Potential causal relationships were evaluated using path analysis. Analyses revealed that a PCOS diagnosis alongside BMI had the largest effect on HRQoL. Higher levels of physical activity (PA) were not associated with greater HRQoL, and PA was not directly affected by any other outcome. However, reduced self-esteem was identified as a key factor in the promotion of physical and mental health.
Original languageEnglish
Pages (from-to)(In-Press)
Number of pages23
JournalWomen's Reproductive Health
Volume(In-Press)
Early online date9 Jan 2024
DOIs
Publication statusE-pub ahead of print - 9 Jan 2024

Bibliographical note

2024 The Author(s). Published with license by Taylor & Francis Group, LLC. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent.

Funder

This study was completed as part of a funded PhD project (CK) through Aston University. This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.

Keywords

  • Physical activity
  • women’s health
  • mental health
  • physical health
  • path analysis
  • self-esteem
  • polycystic ovary syndrome
  • PCOS

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