The effect of vitamin D and/or Calcium supplementation on periodontitis

Mariana Tomaz, Melahat S. Macit, Maria I Niza, Charlote A Jeavons, Berit L Heitmann, Amanda Rodrigues Amorim Adegboye

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: To perform a systematic review and assess whether the use of vitamin D and calcium supplements can benefit the prevention of periodontitis and tooth loss among adults and elderly.
Method: research of MEDLINE, LILACS, Cochrane Library, Scopus and ClinicalTrials.gov and reference lists of relevant papers to identify experimental and observational studies on the effect of vitamin D and/or calcium supplementation on clinical parameters of periodontitis. Primary outcomes were clinical attachment loss (CAL), probing depth (PD) and tooth loss.
Results: Four studies were included. Meta-analysis across studies showed a standardized mean difference (SMD) of –0.194 (95% CI: –0.777 to 0.389) and –0.168 (95% CI: –0.736 to 0.400) for CAL and PD, respectively.
Conclusion: Vitamin D and calcium supplementation seem to have some benefi cial effects on clinical parameters of periodontitis as a complementary therapy. However, these findings need to be confirmed before being used in clinical practice.
Keywords: supplementation; calcium; vitamin D; periodontitis
Original languageEnglish
Pages (from-to)65-81
Number of pages17
JournalInternational Journal of Food Nutrition and Public Health
Volume11
Issue number1/2
DOIs
Publication statusPublished - 3 May 2021
Externally publishedYes

Keywords

  • supplementation
  • calcium
  • vitamin D
  • periodontitis
  • nutrition

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