Abstract
Abstract
Objectives: Cherries are rich in polyphenols and anthocyanins and are believed to possess strong anti inflammatory activity and cardio-protective effects. This study aim was to summarize the overall effect of sour cherry consumption on blood pressure and biomarkers associated with the inflammation.
Methods: MEDLINE/PubMed, Cochrane, and Scopus were searched to find relevant papers up to April 2019. There were no time and language restrictions. This systematic review and meta-analysis was
performed in accordance with the Preferred Items for Reporting of Systematic Reviews and Meta-Analyses (PRISMA) guidelines.
Results: Eleven studies with 275 participants were included in this meta-analysis. Mean dose of the sour cherry was 70 mL/day, whilst mean duration of interventions was six weeks. Combined the results using random-effects model showed significant reductions in diastolic blood pressure levels following sour cherry
consumption (WMD: -2.32mmHg, 95% CI: -4.45, -0.19, I2=39%), but there were no significant changes in systolic blood pressure (WMD: -2.64mmHg, 95% CI: -5.84, 0.56, I2=33%), IL-6 levels (WMD: 0.12 pg/mL, 95% CI: -0.13, 0.36, I2=49%), hs-CRP (WMD: -0.13 mg/mL, 95% CI: -0.47, 0.22, I2=49%) or TNF-α (WMD: -0.07 pg/mL, 95% CI: -0.18, 0.05, I2=00%).
Conclusion: Sour cherry supplementation results a decrease in diastolic blood pressure, but elicits no significant effect on systolic blood pressure, IL-6 levels, CRP levels and TNF-α.
Objectives: Cherries are rich in polyphenols and anthocyanins and are believed to possess strong anti inflammatory activity and cardio-protective effects. This study aim was to summarize the overall effect of sour cherry consumption on blood pressure and biomarkers associated with the inflammation.
Methods: MEDLINE/PubMed, Cochrane, and Scopus were searched to find relevant papers up to April 2019. There were no time and language restrictions. This systematic review and meta-analysis was
performed in accordance with the Preferred Items for Reporting of Systematic Reviews and Meta-Analyses (PRISMA) guidelines.
Results: Eleven studies with 275 participants were included in this meta-analysis. Mean dose of the sour cherry was 70 mL/day, whilst mean duration of interventions was six weeks. Combined the results using random-effects model showed significant reductions in diastolic blood pressure levels following sour cherry
consumption (WMD: -2.32mmHg, 95% CI: -4.45, -0.19, I2=39%), but there were no significant changes in systolic blood pressure (WMD: -2.64mmHg, 95% CI: -5.84, 0.56, I2=33%), IL-6 levels (WMD: 0.12 pg/mL, 95% CI: -0.13, 0.36, I2=49%), hs-CRP (WMD: -0.13 mg/mL, 95% CI: -0.47, 0.22, I2=49%) or TNF-α (WMD: -0.07 pg/mL, 95% CI: -0.18, 0.05, I2=00%).
Conclusion: Sour cherry supplementation results a decrease in diastolic blood pressure, but elicits no significant effect on systolic blood pressure, IL-6 levels, CRP levels and TNF-α.
| Original language | English |
|---|---|
| Pages (from-to) | 1687-1693 |
| Number of pages | 7 |
| Journal | Journal of King Saud University - Computer and Information Sciences |
| Volume | 32 |
| Issue number | 2 |
| Early online date | 9 Jan 2020 |
| DOIs | |
| Publication status | Published - 1 Mar 2020 |
Bibliographical note
This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).Keywords
- Blood pressure
- Inflammation
- Sour cherry
ASJC Scopus subject areas
- General