The effect of propolis on anthropometric indices and lipid profile: a systematic review and meta-analysis of randomized controlled trials

Ammar Salehi-Sahlabadi; Manik Chhabra; Jamal Rahmani; Aref Momeni; Giorgio Karam; Elyas Nattagh-Eshtivani; Mehran Nouri; Cain Clark; Pantea Salehi; Azita Hekmatdoost

doi:10.1007/s40200-020-00604-2

The effect of propolis on anthropometric indices and lipid profile: a systematic review and meta-analysis of randomized controlled trials

Ammar Salehi-Sahlabadi, Manik Chhabra, Jamal Rahmani, Aref Momeni, Giorgio Karam, Elyas Nattagh-Eshtivani, Mehran Nouri, Cain Clark, Pantea Salehi, Azita Hekmatdoost

Research output: Contribution to journal › Review article › peer-review

12 Citations (Scopus)

102 Downloads (Pure)

Abstract

Background & objective(s): The current evidence base regarding the impact of propolis consumption on lipid profile in humans is equivocal. Thus, we sought to investigate the impact of propolis consumption on anthropometric indices and lipid profile in this meta-analysis. Methods: Cochrane Library, Scopus, PubMed, and Web of Science electronic databases were searched up to December 2019. A random-effects model used to pool effect size. The leave-one-out method used to conduct sensitivity analysis. Results: Five RCTs were included in this study. Our findings indicated a significant decrease in triglyceride (TG) (WMD: −3.91 mg/dl, 95% CI: −4.22, −3.60), and a significant increase in high-density lipoprotein (HDL) (WMD: 3.41 mg/dl, 95% CI: 0.05, 6.76), however, for body mass index, weight, cholesterol (CL), and low-density lipoprotein (LDL), no significant alterations were evident. Conclusion: This study revealed that consumption of propolis is associated with a reduction in TG levels, in addition to an increase in HDL levels. Nevertheless, additional research is required to further delineate the relationship between propolis consumption and lipid profile.

Original language	English
Pages (from-to)	1835-1843
Number of pages	9
Journal	Journal of Diabetes and Metabolic Disorders
Volume	19
Issue number	2
Early online date	12 Aug 2020
DOIs	https://doi.org/10.1007/s40200-020-00604-2
Publication status	Published - Dec 2020

Bibliographical note

Copyright © and Moral Rights are retained by the author(s) and/ or other copyright owners. A copy can be downloaded for personal non-commercial research or study, without prior permission or charge. This item cannot be reproduced or quoted extensively from without first obtaining permission in writing from the copyright holder(s). The content must not be changed in any way or sold commercially in any format or medium without the formal permission of the copyright holders.

Keywords

Body mass index
Lipid profile
Propolis
Weight

ASJC Scopus subject areas

Internal Medicine
Endocrinology, Diabetes and Metabolism

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/s40200-020-00604-2

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Salehi-Sahlabadi, A., Chhabra, M., Rahmani, J., Momeni, A., Karam, G., Nattagh-Eshtivani, E., Nouri, M., Clark, C., Salehi, P., & Hekmatdoost, A. (2020). The effect of propolis on anthropometric indices and lipid profile: a systematic review and meta-analysis of randomized controlled trials. Journal of Diabetes and Metabolic Disorders, 19(2), 1835-1843. https://doi.org/10.1007/s40200-020-00604-2

Salehi-Sahlabadi, A, Chhabra, M, Rahmani, J, Momeni, A, Karam, G, Nattagh-Eshtivani, E, Nouri, M, Clark, C, Salehi, P & Hekmatdoost, A 2020, 'The effect of propolis on anthropometric indices and lipid profile: a systematic review and meta-analysis of randomized controlled trials', Journal of Diabetes and Metabolic Disorders, vol. 19, no. 2, pp. 1835-1843. https://doi.org/10.1007/s40200-020-00604-2

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abstract = "Background & objective(s): The current evidence base regarding the impact of propolis consumption on lipid profile in humans is equivocal. Thus, we sought to investigate the impact of propolis consumption on anthropometric indices and lipid profile in this meta-analysis. Methods: Cochrane Library, Scopus, PubMed, and Web of Science electronic databases were searched up to December 2019. A random-effects model used to pool effect size. The leave-one-out method used to conduct sensitivity analysis. Results: Five RCTs were included in this study. Our findings indicated a significant decrease in triglyceride (TG) (WMD: −3.91 mg/dl, 95% CI: −4.22, −3.60), and a significant increase in high-density lipoprotein (HDL) (WMD: 3.41 mg/dl, 95% CI: 0.05, 6.76), however, for body mass index, weight, cholesterol (CL), and low-density lipoprotein (LDL), no significant alterations were evident. Conclusion: This study revealed that consumption of propolis is associated with a reduction in TG levels, in addition to an increase in HDL levels. Nevertheless, additional research is required to further delineate the relationship between propolis consumption and lipid profile.",

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AU - Momeni, Aref

AU - Karam, Giorgio

AU - Nattagh-Eshtivani, Elyas

AU - Nouri, Mehran

AU - Clark, Cain

AU - Salehi, Pantea

AU - Hekmatdoost, Azita

N1 - Copyright © and Moral Rights are retained by the author(s) and/ or other copyright owners. A copy can be downloaded for personal non-commercial research or study, without prior permission or charge. This item cannot be reproduced or quoted extensively from without first obtaining permission in writing from the copyright holder(s). The content must not be changed in any way or sold commercially in any format or medium without the formal permission of the copyright holders.

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N2 - Background & objective(s): The current evidence base regarding the impact of propolis consumption on lipid profile in humans is equivocal. Thus, we sought to investigate the impact of propolis consumption on anthropometric indices and lipid profile in this meta-analysis. Methods: Cochrane Library, Scopus, PubMed, and Web of Science electronic databases were searched up to December 2019. A random-effects model used to pool effect size. The leave-one-out method used to conduct sensitivity analysis. Results: Five RCTs were included in this study. Our findings indicated a significant decrease in triglyceride (TG) (WMD: −3.91 mg/dl, 95% CI: −4.22, −3.60), and a significant increase in high-density lipoprotein (HDL) (WMD: 3.41 mg/dl, 95% CI: 0.05, 6.76), however, for body mass index, weight, cholesterol (CL), and low-density lipoprotein (LDL), no significant alterations were evident. Conclusion: This study revealed that consumption of propolis is associated with a reduction in TG levels, in addition to an increase in HDL levels. Nevertheless, additional research is required to further delineate the relationship between propolis consumption and lipid profile.

AB - Background & objective(s): The current evidence base regarding the impact of propolis consumption on lipid profile in humans is equivocal. Thus, we sought to investigate the impact of propolis consumption on anthropometric indices and lipid profile in this meta-analysis. Methods: Cochrane Library, Scopus, PubMed, and Web of Science electronic databases were searched up to December 2019. A random-effects model used to pool effect size. The leave-one-out method used to conduct sensitivity analysis. Results: Five RCTs were included in this study. Our findings indicated a significant decrease in triglyceride (TG) (WMD: −3.91 mg/dl, 95% CI: −4.22, −3.60), and a significant increase in high-density lipoprotein (HDL) (WMD: 3.41 mg/dl, 95% CI: 0.05, 6.76), however, for body mass index, weight, cholesterol (CL), and low-density lipoprotein (LDL), no significant alterations were evident. Conclusion: This study revealed that consumption of propolis is associated with a reduction in TG levels, in addition to an increase in HDL levels. Nevertheless, additional research is required to further delineate the relationship between propolis consumption and lipid profile.

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The effect of propolis on anthropometric indices and lipid profile: a systematic review and meta-analysis of randomized controlled trials

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

UN SDGs

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