The effect of propolis on anthropometric indices and lipid profile: a systematic review and meta-analysis of randomized controlled trials

Ammar Salehi-Sahlabadi, Manik Chhabra, Jamal Rahmani, Aref Momeni, Giorgio Karam, Elyas Nattagh-Eshtivani, Mehran Nouri, Cain Clark, Pantea Salehi, Azita Hekmatdoost

    Research output: Contribution to journalReview articlepeer-review

    7 Citations (Scopus)
    61 Downloads (Pure)


    Background & objective(s): The current evidence base regarding the impact of propolis consumption on lipid profile in humans is equivocal. Thus, we sought to investigate the impact of propolis consumption on anthropometric indices and lipid profile in this meta-analysis. Methods: Cochrane Library, Scopus, PubMed, and Web of Science electronic databases were searched up to December 2019. A random-effects model used to pool effect size. The leave-one-out method used to conduct sensitivity analysis. Results: Five RCTs were included in this study. Our findings indicated a significant decrease in triglyceride (TG) (WMD: −3.91 mg/dl, 95% CI: −4.22, −3.60), and a significant increase in high-density lipoprotein (HDL) (WMD: 3.41 mg/dl, 95% CI: 0.05, 6.76), however, for body mass index, weight, cholesterol (CL), and low-density lipoprotein (LDL), no significant alterations were evident. Conclusion: This study revealed that consumption of propolis is associated with a reduction in TG levels, in addition to an increase in HDL levels. Nevertheless, additional research is required to further delineate the relationship between propolis consumption and lipid profile.

    Original languageEnglish
    Pages (from-to)1835-1843
    Number of pages9
    JournalJournal of Diabetes and Metabolic Disorders
    Issue number2
    Early online date12 Aug 2020
    Publication statusPublished - Dec 2020

    Bibliographical note

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    • Body mass index
    • Lipid profile
    • Propolis
    • Weight

    ASJC Scopus subject areas

    • Internal Medicine
    • Endocrinology, Diabetes and Metabolism


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