The effect of Pimpinella Anisum herbal tea on human milk volume and weight gain in the preterm infant: a randomized controlled clinical trial

Sona Khalili, Leila Amiri-Farahani, Shima Haghani, Arash Bordbar, Asie Shojaii, Sally Pezaro

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    Abstract

    Background and aims: Human milk supports pre-term infants to thrive. Yet human milk production can be inhibited when infants are born prematurely. Pimpinella Anisum has been evidenced to increase milk production and infant weight gain in previous animal studies. The present study aimed to determine the effect of Pimpinella Anisum herbal tea on human milk volume and preterm infant weight in human populations for the first time. Methods: Human milk supports pre-term infants to thrive. Yet human milk production can be inhibited when infants are born prematurely. Pimpinella Anisum has been evidenced to increase milk production and infant weight gain in previous animal studies. The present study aimed to determine the effect of Pimpinella Anisum herbal tea on human milk volume and preterm infant weight in human populations for the first time. Results: There was a statistically significant difference in terms of milk volume in the first, third, fourth, fifth, sixth and seventh days between the three groups of intervention, placebo, and control (p < 0.05). On the first day, the mean volume of pumped milk in the intervention group was significantly higher than the control group (p = 0.008). On the second day, there was no statistically significant difference between groups. On the third, fourth, fifth, sixth and seventh days, the mean volume of pumped milk in the intervention group was significantly higher than the placebo and control groups (p < 0.05). There was no statistically significant difference in terms of preterm infant weight on days 0, 3 and 7 between the three groups. Conclusion: The use of Pimpinella Anisum or ‘Anise’ tea can increase the volume of human milk and since no specific side effects have been reported in its use, it may be incorporated easily, cheaply, and effectively in practice where appropriate to the benefit of preterm infant nutrition worldwide.
    Original languageEnglish
    Article number19
    Number of pages11
    JournalBMC Complementary Medicine and Therapies
    Volume23
    Issue number1
    Early online date21 Jan 2023
    DOIs
    Publication statusE-pub ahead of print - 21 Jan 2023

    Bibliographical note

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    Keywords

    • Research
    • Pimpinella anisum
    • Breast milk production
    • Milk volume
    • Preterm infants
    • Galactagogue herbal tea
    • Newborn weight
    • Lactation
    • Human milk
    • Breastfeeding

    ASJC Scopus subject areas

    • Complementary and alternative medicine

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