The effect of Okra (Abelmoschus esculentus) on lipid profiles and glycemic indices in type 2 diabetic adults: randomized double blinded trials

Arezoo Moradi, Moahammad-Javad Tarrahi, Sara Ghasempour , Mohammadreza Shafiepour, Cain Clark, Sayyed Morteza Safavi

Research output: Contribution to journalArticle

Abstract

The aim of the present study was to investigate the effect of okra consumption on serum levels of lipid profiles and glycemic indices in Type 2 diabetic (T2D) patients. The present study was a randomized, double-blinded clinical trial, carried out in Kerman, Iran. Sixty T2D patients were randomized into intervention and control groups and received 10 g okra powder blended in 150 g conventional yogurt or conventional yogurt alone, along with dinner and lunch, for 8 weeks. Glycemic markers and lipid profile were assessed, as well as anthropometric measures, at the beginning and end of study. The findings showed that 8 weeks okra consumption resulted in a significant decrease in fasting plasma glucose (−15.61 ± 19.44 vs. −3.40 ± 24.78; p =.02), homeostatic model of assessment for insulin resistance (−1.17 ± 1.61 vs. −0.14 ± 1.64; p =.01), quantitative insulin sensitivity check index (0.01 ± 0.007 vs. 0.00 ± 0.01; p =.004), triacylglycerol (−22.30 ± 32.46 vs. −3.86 ± 30.57; p =.001), total cholesterol (−10.23 ± 10.36 vs. −2.03 ± 13.94; p =.004), low-density lipoprotein cholesterol (LDL-C; −8.15 ± 10.01 vs. −2.31 ± 9.37; p =.02), and LDL-C/high-density lipoprotein cholesterol (HDL-C) ratio (−0.28 ± 0.37 vs. −0.08 ± 0.24; p =.01). No significant difference was observed between groups in HDL-C, glycated hemoglobin, fasting insulin levels, and anthropometric measures. The present study suggests that okra consumption can elicit improvements in lipid profile, as well as glycemic markers, among T2D patients.

Original languageEnglish
Pages (from-to)(In-press)
JournalPhytotherapy Research
Volume(In-press)
Early online date24 Jul 2020
DOIs
Publication statusE-pub ahead of print - 24 Jul 2020

Keywords

  • Abelmoschus esculentus
  • diabetics mellitus
  • glycemic indices
  • lipid profiles
  • trials

ASJC Scopus subject areas

  • Pharmacology

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