The effect of Aronia consumption on lipid profile, blood pressure, and biomarkers of inflammation: a systematic review and meta-analysis of randomized controlled trials

Jamal Rahmani, Cain Clark, Hamed Kord Varkaneh, Theophilus Lakiang, Lenny T. Vasanthan, V Onyeche, Seyyed Mohammad Mousavi, Y. Zhang

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1 Citation (Scopus)


Plant derivatives, such as anthocyanin-rich phytochemicals, have been reported to elicit a positive effect on lipid profile. Therefore, the aim of this study was to systematically review and meta-analyze the effects of Aronia consumption on lipid profiles, blood pressure, and biomarkers of inflammation in randomized controlled trials. A systematic search was performed in PubMed/MEDLINE, Cochrane, and SCOPUS up to December 2018. Seven studies were identified and analyzed in this meta-analysis. Our study found a significant increase in high-density lipoprotein (HDL; weighted mean difference [WMD]: 1.48 mg/dl, 95% confidence interval, CI, [1.29, 1.68]) and diastolic blood pressure (WMD: 2.55 mmHg, 95% CI [0.63, 4.47]) following Aronia consumption. There was no significant effect on systolic blood pressure and C-reactive protein, tumor necrosis factor, and interleukin-1. Furthermore, subgroup analysis showed that cholesterol (WMD: −7.18, 95% CI [−13.90, −0.46]) and low-density lipoprotein (LDL; WMD: −5.84, 95% CI [−6.91, −4.77]) decreased more significantly in interventions less than 10 weeks in duration. Dose–response analysis demonstrated a significant reduction in triglyceride levels when dose of Aronia was increased to 300 mg/day. In conclusion, the results demonstrated a significant increase in HDL and reduction in total cholesterol and LDL among patients supplementing with Aronia.

Original languageEnglish
Pages (from-to)1981-1990
Number of pages10
JournalPhytotherapy Research
Issue number8
Early online date24 Jun 2019
Publication statusPublished - Aug 2019



  • Aronia
  • Chokeberry
  • Blood Pressure
  • Triglyceride
  • Cholesterol
  • CRP

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