The effect of almonds consumption on Blood pressure: A systematic review and dose-response meta-analysis of randomized control trials

Zhe Li, Akshaya Srikanth Bhagavathula, Mitchell Batav, Cain Clark, hebatullah Abdulazeem, Jamal Rahmani, Fuyu Yin

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Almond is rich in antioxidants and phytochemicals such as methylquercetin, protocatechuic acid, catechin, flavonoids, p-hydroxybenzoic acid, resveratrol, vanillic acid, and kaempferol. The aim of the present study was to systematically review and dose-response meta-analyses the effects of almond consumption on systolic and diastolic blood pressure (SBP/DBP), respectively, in Randomized Controlled Trials (RCTs). A systematic search was performed in PubMed/MEDLINE, web of sciences and SCOPUS by 2 researchers, independently to identify randomised controlled trials up to July 2019. There were no time or language restrictions. PRISMA guidelines were followed in conducting
this meta-analysis. Fifteen studies with 21 arms, containing 853 participants, reported SBP as an outcome measure. Pooled results showed significant reduction in SBP (WMD: -0.90 mmHg, 95% CI: -1.74, -0.06, P heterogeneity=0.94) by almond intervention. There is no significant effect from almond consumption on DBP
(WMD: 0.67 mmHg, 95% CI: -1.93, 0.60, P heterogeneity=0.001). Meta-regression analysis showed dose of used almond (g/d) as source of heterogeneity between results of DBP. In conclusion results of this meta-analysis showed reduce effect of Almonds on systolic blood pressure.
Original languageEnglish
Pages (from-to)1757-1763
Number of pages7
JournalJournal of King Saud University - Computer and Information Sciences
Issue number2
Early online date14 Jan 2020
Publication statusPublished - 1 Mar 2020



  • almond
  • systolic blood pressure
  • diastolic blood pressure
  • meta-analysis

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