The effect of adult familiarity and nature of interaction on social anxiety and motivation in Fragile X, Rubinstein-Taybi and Cornelia de Lange syndromes.

Increased social anxiety, alongside a willingness to interact, have been reported to describe the social impairments in individuals with Fragile X (FXS) and Cornelia de Lange (CdLS) syndrome, whereas typical social interest and intact social skills are reported in individuals with Rubinstein-Taybi syndrome (RTS). Understanding situations in which social anxiety may be induced is important for intervention planning. In this study, the effects of adult familiarity and type of social interaction on anxiety and motivation were investigated.