The association of dietary approaches to stop hypertension (DASH) with the odds of diabetic nephropathy and metabolic markers in women: a case–control study

Atieh Mirzababaei, Faezeh Abaj, Sara Hajishizari, Niki Bahrampour, Sahar Noori, Ahmad Mujtaba Barekzai, Dorsa Hosseininasab, Cain C.T. Clark, Khadijeh Mirzaei

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    Abstract

    Objectives: Epidemiologic studies have reported that diet is associated with diabetes and its complications through different pathways. We sought to examine the associations between the Dietary Approaches to Stop Hypertension (DASH) diet and the odds of diabetic nephropathy (DN) developing in Iranian women with existing type 2 diabetes. Methods: In this case–control study, 105 women with DN and 105 controls, matched for age and diabetes duration, were selected from the Kowsar Diabetes Clinic in Semnan, Iran. DASH, estimated using dietary intake, was assessed using a validated and reliable food frequency questionnaire with 147 items. Anthropometric measurements were assessed for all subjects. Logistic regression was performed to examine the association between DASH and the odds of developing DN. Results: After controlling for potential confounders, subjects in the highest intake of DASH diet adherence have 84% lower odds of DN, compared to those with the lowest intake (OR = 0.16, 95% CI = 0.07–0.34, P < 0.001). Among DASH diet subcategories, intakes of vegetables (80%), fruits (88%), nuts and legumes (87%), and low-fat dairy (73%) decreased the risk of DN after adjustment for confounders (P < 0.001). Conclusions: This study showed that the DASH diet is associated with lower odds of DN development in women with type 2 diabetes.

    Original languageEnglish
    Article number63
    JournalBMC Women's Health
    Volume23
    Issue number1
    DOIs
    Publication statusPublished - 12 Feb 2023

    Bibliographical note

    Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

    Funder

    This work was supported by the Tehran University of Medical Sciences (Grant Number: 94-04-161-31155).

    Publisher Copyright:
    © 2023, The Author(s).

    Keywords

    • Case–control
    • Diabetic nephropathy
    • Dietary approaches to stop hypertension

    ASJC Scopus subject areas

    • Reproductive Medicine
    • Obstetrics and Gynaecology

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