Abstract
Background: Migraine is an episodic disorder and a frequent form of headache. An impaired balance between free radical production and an impaired antioxidant defense system leading to oxidative damage may play a major role in migraine etiology. We sought to investigate whether dietary antioxidant quality score (DAQS) is associated with migraine intensity and frequency among women suffering from migraine. Methods: This cross-sectional study was conducted on 265 women. The data related to anthropometric measures and dietary intake were collected. DAQS score was calculated based on FFQ (food frequency questionnaire) vs. the reference daily intake (RDI) quantity. To measure migraine intensity, the migraine disability assessment questionnaire (MIDAS) and visual analog scale (VAS) were used. The frequency of headaches was defined as the days the participants had headaches in the last month and a 30-day headache diary was used. Results: The results of the study demonstrated that VAS, MIDAS, and frequency of headaches were reduced significantly from the low DAQS (poor quality of antioxidants) to high DAQS (high quality of antioxidants) after adjusting covariates. Also, multinomial regression showed there was an inverse association between higher DAQS and the frequency of headaches. In the adjusted model, subjects with the higher DAQS were 69% less likely to have moderate migraine disability, compared with those with the lower DAQS. Linear regression showed, there was an inverse association between vitamin C intake and the grades of pain severity.َAlso in a crude model, a negative association was found between vitamin E and the frequency of headaches. Conclusion: In conclusion, Participants with higher DAQS had lower migraine intensity and headache frequency. In addition, the consumption of vitamin C may potentially associate with decreasing the severity of headaches. Dietary antioxidants should be monitored closely in individuals suffering from migraine.
| Original language | English |
|---|---|
| Article number | 497 |
| Number of pages | 12 |
| Journal | BMC Women's Health |
| Volume | 24 |
| Issue number | 1 |
| Early online date | 9 Sept 2024 |
| DOIs | |
| Publication status | E-pub ahead of print - 9 Sept 2024 |
Bibliographical note
© The Author(s) 2024. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use,sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and
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Funder
The research is financially supported by the Tehran University of Medical Sciences. (Grants ID: 95-01-103-31348)Funding
The research is financially supported by the Tehran University of Medical Sciences. (Grants ID: 95-01-103-31348)
| Funders | Funder number |
|---|---|
| Tehran University of Medical Sciences | (Grants ID: 95-01-103-31348) |
Keywords
- Migraine disability
- Visual analog scale
- DAQS
- Migraine headache