Abstract
Comparison of the timing of appearance of certain T-cell markers in the intrathymic development o f T cells during gestation reveals a common sequence of expression in several species. Here Richard Aspinall and colleagues put forward a hypothesis concerning this 'invariant series' o f markers that shares the same timing o f expression across species barriers. It is proposed that T-cell markers that are members o f the invariant series are very important in deciding the fate of a developing thymocyte.
Original language | English |
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Pages (from-to) | 7-10 |
Number of pages | 4 |
Journal | Immunology Today |
Volume | 12 |
Issue number | 1 |
DOIs | |
Publication status | Published - Jan 1991 |
Externally published | Yes |
ASJC Scopus subject areas
- Immunology