Despite the considerable concentration on sustainable supply chain management (SSCM) among manufacturing organizations, Iranian manufacturing companies are still in the initial stage. Due to significant development in manufacturing industries in Iran, environmental concerns have become the highest concerns for stakeholders. SSCM practices have a straightforward linkage with environmental performance. Consequently, this question was raised that what are the impacts of adopting SSCM practices on environmental performance (EP) in Iranian manufacturing companies? According to the results of this study, the following outcomes have obtained: there is a positive relationship between sustainable purchasing and sustainable logistics and internal environmental management (IEM). On the contrary, sustainable production and sustainable design have not a significant relationship with IEM. In addition, the findings indicate the positive and significant effect of SSCM practices on EP.