Structure/function studies on receptors for vasopressin and oxytocin

M. Wheatley, S. R. Hawtin, N. J. Yarwood

Research output: Chapter in Book/Report/Conference proceedingChapter

9 Citations (Scopus)

Abstract

The neurohypophysial hormones oxytocin (OT) and vasopressin (AVP) mediate their physiological role through interaction with specific receptors. The cloning of OT receptors (OTRs) and AVP receptors (VPRs) from several species has revealed the existence of four receptor subtypes (OT, V1a, V1b and V2). Sequence analysis of these cloned receptors has confirmed that they belong to the G-protein-coupled receptor (GPCR) family, characterised by seven hydrophobic αÁ-helical transmembrane (TM) domains.
Original languageEnglish
Title of host publicationVasopressin and Oxytocin
PublisherSpringer Verlag
Chapter46
Pages363-365
Number of pages3
ISBN (Electronic)978-1-4613-7210-3
ISBN (Print)978-1-4615-4871-3
DOIs
Publication statusPublished - 1998
Externally publishedYes

Publication series

NameAdvances in Experimental Medicine and Biology
PublisherSpringer
Volume449
ISSN (Print)0065-2598

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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