Significance of “The Insulcagon Pump” in the Treatment of Diabetes

To remain the body in homeostasis state, the negative and positive feedback system of the body should be properly working. Insulin acts as a negative feedback and glucagon act as a positive feedback for maintaining glucose concentration in the body. Due to malfunctioning of alpha cells in Type1 diabetes insulin does not produce; therefore, unbalancing occurs in body system. Implicitly, in hyperglycemia, blood glucose level is higher where-as in hypoglycemia blood glucose level is lower than normal values respectively in the body. Hence, insulin is used in hyperglycemia and glucagon in hypoglycemia. Conventially, in Type-1 diabetic, hyperglycemia is treated by using the insulin pumps, injections and pens. Significantly, there is not any such pump available aimed for the treatment of both conditions simultaneously, where-as our designed prototype named as ‘Insulcagon pump’. posses both features, insulin as well as glucagon pumps. In this prototype, we have used invitro continuous glucose sensor which senses the blood glucose level, whose output goes to micro controller which decides to which pump to be activated viz either insulin or glucagon pump in order to maintain the normal values, then inject the required amount of dose into the patient. Our system also contains air bubble and blood bleak detectors for patient safety. This device is applied on a diabetic patient, albino rat, suffering from hypo as well as hyper glycemia. After few days of monitoring associated with treatment, we got adequate results which are presented in graphical form in this paper. It is believed, that our designed prototype will be beneficial for the biomedical research and will lead to enhance the functionality as well reduction in physical size matching with the requirements of American Diabetes Association.