Sex-specific associations between self-reported sleep characteristics and 10-year cardiovascular disease risk in men and women of African descent living in a low socioeconomic status environment

Philippa Forshaw; Arron T.L. Correia; Laura Roden; Estelle V Lambert; Brian T. Layden; Sirimon Reutrakul; Stephanie J. Crowley; Amy Luke; Lara R. Dugas; Dale E. Rae

doi:10.1016/j.sleepe.2024.100091

Sex-specific associations between self-reported sleep characteristics and 10-year cardiovascular disease risk in men and women of African descent living in a low socioeconomic status environment

Philippa Forshaw, Arron T.L. Correia, Laura Roden, Estelle V Lambert, Brian T. Layden, Sirimon Reutrakul, Stephanie J. Crowley, Amy Luke, Lara R. Dugas, Dale E. Rae

Centre for Health and Life Sciences

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

26 Downloads (Pure)

Abstract

Background: Risk factors for cardiovascular disease (CVD) and sleep health are well-known to be sex- and race-specific. To build on the established relationship between sleep duration and CVD risk, this cross-sectional study aimed to describe sex-specific associations between CVD risk and other sleep characteristics (sleep quality, sleep timing and sleep onset latency) in low-income adults of African descent. Methods: Self-reported sleep (Pittsburgh Sleep Quality Index [PSQI], Epworth Sleepiness Scale [ESS], Insomnia Severity Index [ISI]), demographic and lifestyle data were collected in 412 adults (56 % women, 35.0 ± 7.6y, 40 % employed) living in an informal settlement in South Africa. CVD risk was determined using the BMI-modified Framingham 10-year CVD risk formula. Results: Logistic regression analyses, adjusted for employment, alcohol use and physical activity, indicated that men reporting poor sleep quality (OR: 1.95[95 %CI: 1.07–3.51], p=0.025) and earlier bedtimes (0.54[0.39–0.74], p<0.001) were more likely to belong to a higher 10-year CVD risk score quintile. Women reporting earlier bedtimes (0.72[0.55–0.95], p=0.020) and wake-up times (0.30[0.13–0.73], p=0.007), longer sleep-onset latency (1.47[1.43–1.88], p=0.003), shorter total sleep times (0.84[0.72–0.98], p=0.029), higher PSQI global scores (1.93[1.29–2.90], p=0.001) and more moderate to severe symptoms of insomnia (ISI≥15)(3.24[1.04–10.04], p=0.016) were more likely to belong to higher 10-year CVD risk score quintile. Conclusion: In addition to sleep duration, we found that sleep quality, sleep timing and sleep onset latency are additional risk factors for CVD in adults of African descent. Sex-specific differences in the sleep-CVD-risk relationship observed suggests that future studies and recommendations about sleep health in relation to CVD should take sex into account.

Original language	English
Article number	100091
Number of pages	7
Journal	Sleep Epidemiology
Volume	4
Early online date	8 Jul 2024
DOIs	https://doi.org/10.1016/j.sleepe.2024.100091
Publication status	Published - Dec 2024

Bibliographical note

Open access CC-BY

Funder

This work was supported by the National Institute of Health (NIH) (Grant no: DK-111848 and HL-148271). PEF is supported by the National Research Foundation of South Africa (Grant no. PMDS22052514438) and the University of Cape Town Doctoral Research Scholarship. BTL is supported by NIH R01DK104927, P30DK020595, and VA merit 1I01BX003382. ATLC is supported by the National Research Foundation of South Africa (Grant no. 122508 and PMDS22070431438).

Funding

This work was supported by the National Institute of Health (NIH) (Grant no: DK-111848 and HL-148271). PEF is supported by the National Research Foundation of South Africa (Grant no. PMDS22052514438) and the University of Cape Town Doctoral Research Scholarship. BTL is supported by NIH R01DK104927, P30DK020595, and VA merit 1I01BX003382. ATLC is supported by the National Research Foundation of South Africa (Grant no. 122508 and PMDS22070431438).

Funders	Funder number
National Institutes of Health	DK-111848, HL-148271, R01DK104927, P30DK020595
National Research Foundation	PMDS22052514438, 122508, PMDS22070431438
University of Cape Town

Keywords

Sleep health
Socioeconomic status
Circadian rhythms
Sex differences

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.sleepe.2024.100091Licence: CC BY

Roden2024VoRFinal published version, 815 KBLicence: CC BY

Cite this

Forshaw, P., Correia, A. T. L., Roden, L., Lambert, E. V., Layden, B. T., Reutrakul, S., Crowley, S. J., Luke, A., Dugas, L. R., & Rae, D. E. (2024). Sex-specific associations between self-reported sleep characteristics and 10-year cardiovascular disease risk in men and women of African descent living in a low socioeconomic status environment. Sleep Epidemiology, 4, Article 100091. https://doi.org/10.1016/j.sleepe.2024.100091

Sex-specific associations between self-reported sleep characteristics and 10-year cardiovascular disease risk in men and women of African descent living in a low socioeconomic status environment. / Forshaw, Philippa; Correia, Arron T.L.; Roden, Laura et al.
In: Sleep Epidemiology, Vol. 4, 100091, 12.2024.

Research output: Contribution to journal › Article › peer-review

Forshaw, P, Correia, ATL, Roden, L, Lambert, EV, Layden, BT, Reutrakul, S, Crowley, SJ, Luke, A, Dugas, LR & Rae, DE 2024, 'Sex-specific associations between self-reported sleep characteristics and 10-year cardiovascular disease risk in men and women of African descent living in a low socioeconomic status environment', Sleep Epidemiology, vol. 4, 100091. https://doi.org/10.1016/j.sleepe.2024.100091

@article{90812f0d68fb4d9ca22de69725c6ce1f,

title = "Sex-specific associations between self-reported sleep characteristics and 10-year cardiovascular disease risk in men and women of African descent living in a low socioeconomic status environment",

abstract = "Background: Risk factors for cardiovascular disease (CVD) and sleep health are well-known to be sex- and race-specific. To build on the established relationship between sleep duration and CVD risk, this cross-sectional study aimed to describe sex-specific associations between CVD risk and other sleep characteristics (sleep quality, sleep timing and sleep onset latency) in low-income adults of African descent. Methods: Self-reported sleep (Pittsburgh Sleep Quality Index [PSQI], Epworth Sleepiness Scale [ESS], Insomnia Severity Index [ISI]), demographic and lifestyle data were collected in 412 adults (56 % women, 35.0 ± 7.6y, 40 % employed) living in an informal settlement in South Africa. CVD risk was determined using the BMI-modified Framingham 10-year CVD risk formula. Results: Logistic regression analyses, adjusted for employment, alcohol use and physical activity, indicated that men reporting poor sleep quality (OR: 1.95[95 %CI: 1.07–3.51], p=0.025) and earlier bedtimes (0.54[0.39–0.74], p<0.001) were more likely to belong to a higher 10-year CVD risk score quintile. Women reporting earlier bedtimes (0.72[0.55–0.95], p=0.020) and wake-up times (0.30[0.13–0.73], p=0.007), longer sleep-onset latency (1.47[1.43–1.88], p=0.003), shorter total sleep times (0.84[0.72–0.98], p=0.029), higher PSQI global scores (1.93[1.29–2.90], p=0.001) and more moderate to severe symptoms of insomnia (ISI≥15)(3.24[1.04–10.04], p=0.016) were more likely to belong to higher 10-year CVD risk score quintile. Conclusion: In addition to sleep duration, we found that sleep quality, sleep timing and sleep onset latency are additional risk factors for CVD in adults of African descent. Sex-specific differences in the sleep-CVD-risk relationship observed suggests that future studies and recommendations about sleep health in relation to CVD should take sex into account.",

keywords = "Sleep health, Socioeconomic status, Circadian rhythms, Sex differences",

author = "Philippa Forshaw and Correia, {Arron T.L.} and Laura Roden and Lambert, {Estelle V} and Layden, {Brian T.} and Sirimon Reutrakul and Crowley, {Stephanie J.} and Amy Luke and Dugas, {Lara R.} and Rae, {Dale E.}",

note = "Open access CC-BY",

year = "2024",

month = dec,

doi = "10.1016/j.sleepe.2024.100091",

language = "English",

volume = "4",

journal = "Sleep Epidemiology",

issn = "2667-3436",

publisher = "Elsevier",

}

TY - JOUR

T1 - Sex-specific associations between self-reported sleep characteristics and 10-year cardiovascular disease risk in men and women of African descent living in a low socioeconomic status environment

AU - Forshaw, Philippa

AU - Correia, Arron T.L.

AU - Roden, Laura

AU - Lambert, Estelle V

AU - Layden, Brian T.

AU - Reutrakul, Sirimon

AU - Crowley, Stephanie J.

AU - Luke, Amy

AU - Dugas, Lara R.

AU - Rae, Dale E.

N1 - Open access CC-BY

PY - 2024/12

Y1 - 2024/12

N2 - Background: Risk factors for cardiovascular disease (CVD) and sleep health are well-known to be sex- and race-specific. To build on the established relationship between sleep duration and CVD risk, this cross-sectional study aimed to describe sex-specific associations between CVD risk and other sleep characteristics (sleep quality, sleep timing and sleep onset latency) in low-income adults of African descent. Methods: Self-reported sleep (Pittsburgh Sleep Quality Index [PSQI], Epworth Sleepiness Scale [ESS], Insomnia Severity Index [ISI]), demographic and lifestyle data were collected in 412 adults (56 % women, 35.0 ± 7.6y, 40 % employed) living in an informal settlement in South Africa. CVD risk was determined using the BMI-modified Framingham 10-year CVD risk formula. Results: Logistic regression analyses, adjusted for employment, alcohol use and physical activity, indicated that men reporting poor sleep quality (OR: 1.95[95 %CI: 1.07–3.51], p=0.025) and earlier bedtimes (0.54[0.39–0.74], p<0.001) were more likely to belong to a higher 10-year CVD risk score quintile. Women reporting earlier bedtimes (0.72[0.55–0.95], p=0.020) and wake-up times (0.30[0.13–0.73], p=0.007), longer sleep-onset latency (1.47[1.43–1.88], p=0.003), shorter total sleep times (0.84[0.72–0.98], p=0.029), higher PSQI global scores (1.93[1.29–2.90], p=0.001) and more moderate to severe symptoms of insomnia (ISI≥15)(3.24[1.04–10.04], p=0.016) were more likely to belong to higher 10-year CVD risk score quintile. Conclusion: In addition to sleep duration, we found that sleep quality, sleep timing and sleep onset latency are additional risk factors for CVD in adults of African descent. Sex-specific differences in the sleep-CVD-risk relationship observed suggests that future studies and recommendations about sleep health in relation to CVD should take sex into account.

AB - Background: Risk factors for cardiovascular disease (CVD) and sleep health are well-known to be sex- and race-specific. To build on the established relationship between sleep duration and CVD risk, this cross-sectional study aimed to describe sex-specific associations between CVD risk and other sleep characteristics (sleep quality, sleep timing and sleep onset latency) in low-income adults of African descent. Methods: Self-reported sleep (Pittsburgh Sleep Quality Index [PSQI], Epworth Sleepiness Scale [ESS], Insomnia Severity Index [ISI]), demographic and lifestyle data were collected in 412 adults (56 % women, 35.0 ± 7.6y, 40 % employed) living in an informal settlement in South Africa. CVD risk was determined using the BMI-modified Framingham 10-year CVD risk formula. Results: Logistic regression analyses, adjusted for employment, alcohol use and physical activity, indicated that men reporting poor sleep quality (OR: 1.95[95 %CI: 1.07–3.51], p=0.025) and earlier bedtimes (0.54[0.39–0.74], p<0.001) were more likely to belong to a higher 10-year CVD risk score quintile. Women reporting earlier bedtimes (0.72[0.55–0.95], p=0.020) and wake-up times (0.30[0.13–0.73], p=0.007), longer sleep-onset latency (1.47[1.43–1.88], p=0.003), shorter total sleep times (0.84[0.72–0.98], p=0.029), higher PSQI global scores (1.93[1.29–2.90], p=0.001) and more moderate to severe symptoms of insomnia (ISI≥15)(3.24[1.04–10.04], p=0.016) were more likely to belong to higher 10-year CVD risk score quintile. Conclusion: In addition to sleep duration, we found that sleep quality, sleep timing and sleep onset latency are additional risk factors for CVD in adults of African descent. Sex-specific differences in the sleep-CVD-risk relationship observed suggests that future studies and recommendations about sleep health in relation to CVD should take sex into account.

KW - Sleep health

KW - Socioeconomic status

KW - Circadian rhythms

KW - Sex differences

UR - http://www.scopus.com/inward/record.url?scp=85198246983&partnerID=8YFLogxK

U2 - 10.1016/j.sleepe.2024.100091

DO - 10.1016/j.sleepe.2024.100091

M3 - Article

SN - 2667-3436

VL - 4

JO - Sleep Epidemiology

JF - Sleep Epidemiology

M1 - 100091

ER -

Sex-specific associations between self-reported sleep characteristics and 10-year cardiovascular disease risk in men and women of African descent living in a low socioeconomic status environment

Abstract

Bibliographical note

Funder

Funding

Keywords

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this