S-acylation by the DHHC protein family

Jennifer Greaves, Luke H Chamberlain

Research output: Contribution to journalReview article

10 Citations (Scopus)

Abstract

A family of 23 DHHC (Asp-His-His-Cys) proteins that function as mammalian S-acyltransferases has been identified, reinvigorating the study of protein S-acylation. Recent studies have continued to reveal how S-acylation affects target proteins, and have provided glimpses of how DHHC-substrate specificity might be achieved.

Original languageEnglish
Pages (from-to)522-524
Number of pages3
JournalBiochemical Society Transactions
Volume38
Issue number2
DOIs
Publication statusPublished - 1 Apr 2010
Externally publishedYes

Fingerprint

Acylation
Acyltransferases
Protein S
Substrate Specificity
Proteins
Substrates

Keywords

  • Acylation
  • Acyltransferases
  • Animals
  • Catalysis
  • Humans
  • Membrane Proteins
  • Multigene Family
  • Proteins
  • Substrate Specificity
  • Tissue Distribution
  • Journal Article
  • Research Support, Non-U.S. Gov't
  • Review

Cite this

S-acylation by the DHHC protein family. / Greaves, Jennifer; Chamberlain, Luke H.

In: Biochemical Society Transactions, Vol. 38, No. 2, 01.04.2010, p. 522-524.

Research output: Contribution to journalReview article

Greaves, Jennifer ; Chamberlain, Luke H. / S-acylation by the DHHC protein family. In: Biochemical Society Transactions. 2010 ; Vol. 38, No. 2. pp. 522-524.
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KW - Acylation

KW - Acyltransferases

KW - Animals

KW - Catalysis

KW - Humans

KW - Membrane Proteins

KW - Multigene Family

KW - Proteins

KW - Substrate Specificity

KW - Tissue Distribution

KW - Journal Article

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