S-acylation by the DHHC protein family

Jennifer Greaves, Luke H Chamberlain

Research output: Contribution to journalReview articlepeer-review

12 Citations (Scopus)


A family of 23 DHHC (Asp-His-His-Cys) proteins that function as mammalian S-acyltransferases has been identified, reinvigorating the study of protein S-acylation. Recent studies have continued to reveal how S-acylation affects target proteins, and have provided glimpses of how DHHC-substrate specificity might be achieved.

Original languageEnglish
Pages (from-to)522-524
Number of pages3
JournalBiochemical Society Transactions
Issue number2
Publication statusPublished - 1 Apr 2010
Externally publishedYes


  • Acylation
  • Acyltransferases
  • Animals
  • Catalysis
  • Humans
  • Membrane Proteins
  • Multigene Family
  • Proteins
  • Substrate Specificity
  • Tissue Distribution
  • Journal Article
  • Research Support, Non-U.S. Gov't
  • Review


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