Role of endothelium in ischaemia-induced myocardial dysfunction of isolated working hearts: cardioprotection by activation of adenosine A2A receptors

H.L. Maddock, K.J. Broadley, A. Bril, N. Khandoudi

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

This study aimed to determine the role of the vascular endothelium on recovery of contractile function following global low‐flow ischaemia of guinea‐pig isolated working hearts and the effects of adenosine analogues on this recovery.
Original languageEnglish
Pages (from-to)263-271
Number of pages9
JournalJournal of Autonomic Pharmacology
Volume21
Issue number5
DOIs
Publication statusPublished - 2001
Externally publishedYes

Keywords

  • adenosine analogues
  • A1 and A2‐purinoceptors
  • endothelium
  • ischaemia and reperfusion
  • working heart
  • cardioprotection

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