Retinopathy in persons with impaired glucose metabolism: the Australian Diabetes Obesity and Lifestyle (AusDiab) study

Tien Y Wong, Elizabeth L M Barr, Robyn J Tapp, C Alex Harper, Hugh R Taylor, Paul Z Zimmet, Jonathan E Shaw

Research output: Contribution to journalArticle

50 Citations (Scopus)

Abstract

PURPOSE: To describe risk factors and vascular disease associations of retinopathy in people with impaired glucose metabolism.

DESIGN: Population-based cross-sectional study.

METHODS: Retinal photographs taken of participants with impaired glucose tolerance and impaired fasting glucose were graded for retinopathy. Risk factors and cardiovascular outcomes were ascertained.

RESULTS: Retinopathy was present in 69 (6.7%) of 1027 participants with impaired glucose tolerance or impaired fasting glucose. After multivariate adjustment, retinopathy was associated with prevalent stroke (odds ratio 4.2, 95% confidence interval, 1.8 to 9.7).

CONCLUSIONS: Retinopathy is common in persons with impaired glucose metabolism and may be associated with prevalent stroke.

Original languageEnglish
Pages (from-to)1157-9
Number of pages3
JournalActa Ophthalmologica
Volume140
Issue number6
DOIs
Publication statusPublished - Dec 2005
Externally publishedYes

Keywords

  • Adult
  • Australia
  • Blood Glucose/metabolism
  • Cross-Sectional Studies
  • Diabetes Complications
  • Female
  • Glucose/metabolism
  • Glucose Intolerance/blood
  • Glucose Tolerance Test
  • Humans
  • Life Style
  • Male
  • Middle Aged
  • Obesity/complications
  • Retinal Diseases/blood
  • Risk Factors
  • Stroke/blood

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