Abstract
The emergence of large language models (LLMs) and generative artificial intelligence (GenAI) has marked a turning point in health informatics. AI has become a very helpful tool for health informatics applications, with numerous AI applications in health informatics being reported in the last years. The objective of this paper is to synthesize the common concerns and opportunities raised by recent popular reviews on AI and health informatics. The main methodological topics covered in this up-to-date review include traditional AI, GenAI, and LLMs. The literature search was conducted through the popular academic database Scopus, which covers over one hundred million records, including both computer science and healthcare. Among these popular reviews (measured by the number of citations that each one received), clinical decision support, patient care, electronic health records, hospital management, and remote patient monitoring are the most mentioned healthcare topics. Different from the majority of the existing reviews that narrowly cover on one to a few topics in healthcare, our review is designed with the objective to provide a broad coverage, such that practitioners may benefit from comprehensive insights covering the above mentioned five popular topics in AI health informatics applications. Based on an in-depth analysis of these reviews by human experts, the main AI tools used, their main challenges, and some future directions have been identified in our investigation. Patient privacy, cybersecurity, ethics, clinical accountability, engaging health professionals, benchmarks and standardization, as well as lack of explainability are the common concerns identified from the literature covered in this review.
| Original language | English |
|---|---|
| Article number | 495 |
| Number of pages | 46 |
| Journal | Healthcare |
| Volume | 14 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 14 Feb 2026 |
Bibliographical note
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) licenseUN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- artificial intelligence
- clinical decision support
- electronic health records
- generative AI
- health analytics
- health informatics
- hospital management
- large language models
- patient care
- remote patient monitoring
ASJC Scopus subject areas
- Leadership and Management
- Health Policy
- Health Informatics
- Health Information Management
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