BACKGROUND: The evidence supporting a relationship between stress and diabetes has been inconsistent.
PURPOSE: This study examined the effects of stress on abnormal glucose metabolism, using a population-based sample of 3,759, with normoglycemia at baseline, from the Australian Diabetes, Obesity and Lifestyle study.
METHODS: Perceived stress and stressful life events were measured at baseline, with health behavior and anthropometric information also collected. Oral glucose tolerance tests were undertaken at baseline and 5-year follow-up. The primary outcome was the development of abnormal glucose metabolism (impaired fasting glucose, impaired glucose tolerance, and type 2 diabetes), according to WHO 1999 criteria.
RESULTS: Perceived stress predicted incident abnormal glucose metabolism in women but not men, after multivariate adjustment. Life events showed an inconsistent relationship with abnormal glucose metabolism.
CONCLUSIONS: Perceived stress predicted abnormal glucose metabolism in women. Healthcare professionals should consider psychosocial adversity when assessing risk factor profiles for the development of diabetes.
|Number of pages||11|
|Journal||Annals of behavioral medicine : a publication of the Society of Behavioral Medicine|
|Early online date||7 Feb 2013|
|Publication status||Published - Aug 2013|
- Blood Glucose/metabolism
- Diabetes Mellitus, Type 2/metabolism
- Glucose Intolerance/metabolism
- Glucose Tolerance Test
- Health Behavior
- Insulin Resistance/physiology
- Life Change Events
- Life Style
- Prediabetic State/metabolism
- Risk Factors
- Stress, Psychological/metabolism