Abstract
The QCA‐1 molecule (quiescent cell antigen‐1) appears to be involved in the differentiation events undergone by T cell following occupancy of the antigen receptor. Here we show that modulation of the QCA‐1 antigen from the surface of the cell normally follows activation, and that treatment of animals with the antibodies against the QCA‐1 molecule inhibits the normal response to an allograft without appearing to alter the number of peripheral T cells or the expression by these cells of the α/β T cell antigen receptor.
| Original language | English |
|---|---|
| Pages (from-to) | 3053-3056 |
| Number of pages | 4 |
| Journal | European Journal of Immunology |
| Volume | 21 |
| Issue number | 12 |
| DOIs | |
| Publication status | Published - Dec 1991 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Immunology and Allergy
- Immunology
Cite this
Prolonged survival of skin grafts following treatment with an antibody to a putative cell triggering molecule, QCA‐1. / Aspinall, Richard; Kampinga, Jaap; Van Den Bogaerde, Johan.
In: European Journal of Immunology, Vol. 21, No. 12, 12.1991, p. 3053-3056.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Prolonged survival of skin grafts following treatment with an antibody to a putative cell triggering molecule, QCA‐1
AU - Aspinall, Richard
AU - Kampinga, Jaap
AU - Van Den Bogaerde, Johan
PY - 1991/12
Y1 - 1991/12
N2 - The QCA‐1 molecule (quiescent cell antigen‐1) appears to be involved in the differentiation events undergone by T cell following occupancy of the antigen receptor. Here we show that modulation of the QCA‐1 antigen from the surface of the cell normally follows activation, and that treatment of animals with the antibodies against the QCA‐1 molecule inhibits the normal response to an allograft without appearing to alter the number of peripheral T cells or the expression by these cells of the α/β T cell antigen receptor.
AB - The QCA‐1 molecule (quiescent cell antigen‐1) appears to be involved in the differentiation events undergone by T cell following occupancy of the antigen receptor. Here we show that modulation of the QCA‐1 antigen from the surface of the cell normally follows activation, and that treatment of animals with the antibodies against the QCA‐1 molecule inhibits the normal response to an allograft without appearing to alter the number of peripheral T cells or the expression by these cells of the α/β T cell antigen receptor.
UR - http://www.scopus.com/inward/record.url?scp=0026044956&partnerID=8YFLogxK
U2 - 10.1002/eji.1830211224
DO - 10.1002/eji.1830211224
M3 - Article
VL - 21
SP - 3053
EP - 3056
JO - European Journal of Immunology
JF - European Journal of Immunology
SN - 0014-2980
IS - 12
ER -