Abstract
S-palmitoylation is a posttranslational modification that regulates membrane-protein interactions. However, palmitate is more than just a hydrophobic membrane anchor, as many different types of protein are palmitoylated, including transmembrane proteins. Indeed, there is now compelling evidence that palmitoylation plays a key role in regulating various aspects of protein sorting within the cell.
| Original language | English |
|---|---|
| Pages (from-to) | 249-254 |
| Number of pages | 6 |
| Journal | Nature Cell Biology |
| Volume | 176 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 29 Jan 2007 |
| Externally published | Yes |
Keywords
- Animals
- Humans
- Palmitic Acids
- Protein Processing, Post-Translational
- Protein Transport
- Journal Article
- Research Support, Non-U.S. Gov't
- Review