Palmitoylation and the trafficking of peripheral membrane proteins

Luke H Chamberlain, Kimon Lemonidis, Maria Sanchez-Perez, Martin W Werno, Oforiwa A Gorleku, Jennifer Greaves

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Palmitoylation, the attachment of palmitate and other fatty acids on to cysteine residues, is a common post-translational modification of both integral and peripheral membrane proteins. Dynamic palmitoylation controls the intracellular distribution of peripheral membrane proteins by regulating membrane-cytosol exchange and/or by modifying the flux of the proteins through vesicular transport systems.

Original languageEnglish
Pages (from-to)62-66
Number of pages5
JournalBiochemical Society Transactions
Volume41
Issue number1
DOIs
Publication statusPublished - 29 Jan 2013

Fingerprint

Lipoylation
Membrane Proteins
Palmitates
Post Translational Protein Processing
Cytosol
Cysteine
Fatty Acids
Fluxes
Membranes
Proteins

Keywords

  • Cell Membrane
  • Golgi Apparatus
  • Lipoylation
  • Membrane Proteins
  • Palmitic Acid
  • Protein Transport
  • Subcellular Fractions
  • Synaptosomal-Associated Protein 25
  • ras Proteins
  • Journal Article
  • Research Support, Non-U.S. Gov't

Cite this

Chamberlain, L. H., Lemonidis, K., Sanchez-Perez, M., Werno, M. W., Gorleku, O. A., & Greaves, J. (2013). Palmitoylation and the trafficking of peripheral membrane proteins. Biochemical Society Transactions, 41(1), 62-66. https://doi.org/10.1042/BST20120243

Palmitoylation and the trafficking of peripheral membrane proteins. / Chamberlain, Luke H; Lemonidis, Kimon; Sanchez-Perez, Maria; Werno, Martin W; Gorleku, Oforiwa A; Greaves, Jennifer.

In: Biochemical Society Transactions, Vol. 41, No. 1, 29.01.2013, p. 62-66.

Research output: Contribution to journalArticle

Chamberlain, LH, Lemonidis, K, Sanchez-Perez, M, Werno, MW, Gorleku, OA & Greaves, J 2013, 'Palmitoylation and the trafficking of peripheral membrane proteins' Biochemical Society Transactions, vol. 41, no. 1, pp. 62-66. https://doi.org/10.1042/BST20120243
Chamberlain LH, Lemonidis K, Sanchez-Perez M, Werno MW, Gorleku OA, Greaves J. Palmitoylation and the trafficking of peripheral membrane proteins. Biochemical Society Transactions. 2013 Jan 29;41(1):62-66. https://doi.org/10.1042/BST20120243
Chamberlain, Luke H ; Lemonidis, Kimon ; Sanchez-Perez, Maria ; Werno, Martin W ; Gorleku, Oforiwa A ; Greaves, Jennifer. / Palmitoylation and the trafficking of peripheral membrane proteins. In: Biochemical Society Transactions. 2013 ; Vol. 41, No. 1. pp. 62-66.
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