Palmitoylation and the trafficking of peripheral membrane proteins

Luke H Chamberlain, Kimon Lemonidis, Maria Sanchez-Perez, Martin W Werno, Oforiwa A Gorleku, Jennifer Greaves

Research output: Contribution to journalArticlepeer-review

29 Citations (Scopus)


Palmitoylation, the attachment of palmitate and other fatty acids on to cysteine residues, is a common post-translational modification of both integral and peripheral membrane proteins. Dynamic palmitoylation controls the intracellular distribution of peripheral membrane proteins by regulating membrane-cytosol exchange and/or by modifying the flux of the proteins through vesicular transport systems.

Original languageEnglish
Pages (from-to)62-66
Number of pages5
JournalBiochemical Society Transactions
Issue number1
Publication statusPublished - 29 Jan 2013


  • Cell Membrane
  • Golgi Apparatus
  • Lipoylation
  • Membrane Proteins
  • Palmitic Acid
  • Protein Transport
  • Subcellular Fractions
  • Synaptosomal-Associated Protein 25
  • ras Proteins
  • Journal Article
  • Research Support, Non-U.S. Gov't


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