Abstract
This paper presents the results arising from a practical implementation of a novel hybrid optimisation scheme, used to solve the inverse problem in radiotherapy treatment planning (RTP). A matrix-based beam model which has been developed making use of a control systems modelling approach is used, together with a hybrid optimisation scheme. Patient-specific compensator profiles are deduced from the intensity modulated beam profiles obtained from the hybrid scheme, with use being made of an exponential attenuation factor coupled with a point spread convolution function to account for the scatter in the compensator. A good agreement between the predicted and actual conformational distributions is achieved.
Original language | English |
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Pages (from-to) | 1739–1745 |
Journal | Control Engineering Practice |
Volume | 5 |
Issue number | 12 |
DOIs | |
Publication status | Published - Dec 1997 |
Bibliographical note
© IFAC 1997. This work is posted here by permission of IFAC for your personal use. Not fordistribution. The original version was published in ifac-papersonline.net, DOI
10.1016/S0967-0661(97)10029-6
Keywords
- Genetic algorithms
- geometric approaches
- inverse problem
- iterative methods
- least squares methods
- multiobjective optimisation
- physics
- systems methodology