Nucleotide sequences of the VP4 and VP7 genes of a Chinese lamb rotavirus: evidence for a new P type in a G10 type virus

S Shen, B Burke, U Desselberger

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Abstract

The VP7 and VP4 genes of a group A rotavirus (Lp14) isolated from a lamb with diarrhea in Qinhai province, China, in 1981 were reverse transcribed, amplified by PCR, cloned, and sequenced. The virus was found to possess a VP7 gene, classifying it as a G10 type, and a VP4 gene which showed only limited homology with any other known VP4 gene, suggesting its classification as a new P type and providing further evidence for the vast diversity of group A rotaviruses.

Original languageEnglish
Pages (from-to)497-500
Number of pages4
JournalVirology
Volume197
Issue number1
DOIs
Publication statusPublished - Nov 1993

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Keywords

  • Amino Acid Sequence
  • Animals
  • Antigens, Viral
  • Base Sequence
  • Capsid/genetics
  • Capsid Proteins
  • Diarrhea/microbiology
  • Genes, Viral
  • Humans
  • Molecular Sequence Data
  • Rotavirus/genetics
  • Sequence Homology, Amino Acid
  • Sequence Homology, Nucleic Acid
  • Sheep
  • Sheep Diseases/microbiology

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