Nucleotide sequences of the VP4 and VP7 genes of a Chinese lamb rotavirus: evidence for a new P type in a G10 type virus

S Shen, B Burke, U Desselberger

    Research output: Contribution to journalArticlepeer-review

    27 Citations (Scopus)

    Abstract

    The VP7 and VP4 genes of a group A rotavirus (Lp14) isolated from a lamb with diarrhea in Qinhai province, China, in 1981 were reverse transcribed, amplified by PCR, cloned, and sequenced. The virus was found to possess a VP7 gene, classifying it as a G10 type, and a VP4 gene which showed only limited homology with any other known VP4 gene, suggesting its classification as a new P type and providing further evidence for the vast diversity of group A rotaviruses.

    Original languageEnglish
    Pages (from-to)497-500
    Number of pages4
    JournalVirology
    Volume197
    Issue number1
    DOIs
    Publication statusPublished - Nov 1993

    Keywords

    • Amino Acid Sequence
    • Animals
    • Antigens, Viral
    • Base Sequence
    • Capsid/genetics
    • Capsid Proteins
    • Diarrhea/microbiology
    • Genes, Viral
    • Humans
    • Molecular Sequence Data
    • Rotavirus/genetics
    • Sequence Homology, Amino Acid
    • Sequence Homology, Nucleic Acid
    • Sheep
    • Sheep Diseases/microbiology

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