Abstract
Background and aim: National Institutes of Clinical Excellence (NICE)’s “at-risk” guidelines (waist-to-height ratio (WC/HT)<0.5) over penalizes shorter adults and fails to alert taller adults who may be at risk. The aim is to assess whether the “at-risk” guidelines recommended by NICE are appropriate for children, by assessing whether their WCs increase in proportion to their height, thus obeying the principle of “geometric similarity.”.
Methods: Cross-sectional study including 11018 participants aged 7-17 years. We assessed whether the children’s waist circumferences (WC) increased in proportion to their heights (HT) using the allometric power law, WC=a.HT^b. We also cross-tabulated children (7-13 yrs.) and adolescents (14-17 yrs.) by height categories (short <145 cm, average 145 to 175 cm, and tall>0.175 cm) to identify whether taller or shorter individuals were equally “at-risk” (WHTR>0.5).
Results: The power law identified children’s height exponents was approximately 1 (geometrically similar), but older adolescents’ height exponents were approximately 0.5. We also identified that the frequency of children “at-risk” was evenly spread across the 3 height groups. In contrast, shorter adolescents were more frequently “at-risk” compared with their taller peers.
Conclusions: NICEs guideline (WC/HT<0.5) is suitable for, and fairly classifies children (aged 7-12 years) “at-risk” irrespective of their height. In contrast, shorter adolescents are consistently more likely to be unfairly classified as “at-risk” compared with taller adolescents, i.e., NICEs guideline (WC/HT<0.5) will unfairly classify many adolescents as being “at-risk”, with shorter adolescents being consistently over-penalized compared with their taller peers who may well be lulled into a false sense of security.
Methods: Cross-sectional study including 11018 participants aged 7-17 years. We assessed whether the children’s waist circumferences (WC) increased in proportion to their heights (HT) using the allometric power law, WC=a.HT^b. We also cross-tabulated children (7-13 yrs.) and adolescents (14-17 yrs.) by height categories (short <145 cm, average 145 to 175 cm, and tall>0.175 cm) to identify whether taller or shorter individuals were equally “at-risk” (WHTR>0.5).
Results: The power law identified children’s height exponents was approximately 1 (geometrically similar), but older adolescents’ height exponents were approximately 0.5. We also identified that the frequency of children “at-risk” was evenly spread across the 3 height groups. In contrast, shorter adolescents were more frequently “at-risk” compared with their taller peers.
Conclusions: NICEs guideline (WC/HT<0.5) is suitable for, and fairly classifies children (aged 7-12 years) “at-risk” irrespective of their height. In contrast, shorter adolescents are consistently more likely to be unfairly classified as “at-risk” compared with taller adolescents, i.e., NICEs guideline (WC/HT<0.5) will unfairly classify many adolescents as being “at-risk”, with shorter adolescents being consistently over-penalized compared with their taller peers who may well be lulled into a false sense of security.
| Original language | English |
|---|---|
| Article number | 104117 |
| Journal | Nutrition, Metabolism and Cardiovascular Diseases |
| Volume | 35 |
| Issue number | 10 |
| Early online date | 8 May 2025 |
| DOIs | |
| Publication status | Published - Oct 2025 |
Funding
This research was supported by the Brazilian Agencies Foundation for Research Support of Rio Grande do Sul (FAPERGS), and the Coordination of Improvement of Higher Level Personnel (CAPES) code number 001.
| Funders | Funder number |
|---|---|
| Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul | |
| Coordenação de Aperfeiçoamento de Pessoal de Nível Superior |
Keywords
- Risk
- Geometric Power Law
- Pediatric
- Obesity
- Weight status