Abstract
Both β-Adrenergic receptor (β-AR) signaling pathway and Ca 2+/Calmodulin-dependent protein kinase II (CaMKII) play important roles in regulating cardiac excitation-contraction coupling. However, the laboratory experiments cannot quantify these regulatory roles easily, computer models have been used as an alternative way. The aim of this study was to use computer models to preliminarily investigate the combined role of β-AR and CaMKII in human cardiac myocyte properties
| Original language | English |
|---|---|
| Pages (from-to) | 389-392 |
| Number of pages | 4 |
| Journal | Computing in Cardiology |
| Publication status | Published - 16 Jan 2014 |
| Externally published | Yes |
| Event | 2013 40th Computing in Cardiology Conference, CinC 2013 - Zaragoza, Spain Duration: 22 Sep 2013 → 25 Sep 2013 |
ASJC Scopus subject areas
- Computer Science(all)
- Cardiology and Cardiovascular Medicine
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Dai, L., Zang, Y., Zheng, D., Luo, R., & Xia, L. (2014). Modelling the integrated regulation role of β-adrenergic signaling and CaMKII in human myocyte electrophysiological properties. Computing in Cardiology, 389-392.