Maze-Out: A Serious Game to Enhance Treatment for Eating Disorders: A Randomised Controlled Trial

Maria Guala, Aida Bikic, Kim Bul, David Clinton, Anna Mejdal, Helene Nygaard Nielsen, René Klinkby Støving, Anette Søgaard Nielsen

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Abstract

Objective:
This study evaluated the effectiveness of Maze Out, a serious game (SG) co-designed by patients with eating disorders (ED) and clinicians as an adjunct to Treatment as Usual (TAU) for improving self-efficacy, self-image, and engagement in individuals with ED. Additionally, the study examined its impact on feelings of ineffectiveness, insecurity, and personal recovery rather than directly targeting broader eating pathology.
Method:
A randomised controlled trial (RCT) was conducted at 11 centres in Denmark between July 2022 and December 2023. A total of 133 participants adults (≥18 years) with a registered ICD-10 ED diagnosis were randomised (1:1) to receive Maze Out plus TAU (intervention) or TAU alone (control) for 15 weeks. Assessments were conducted at baseline, 8 weeks, and 15 weeks. Primary outcome was self-efficacy, while secondary outcomes included self-image, feelings of ineffectiveness and insecurity, and personal recovery. Linear mixed-effects models were used for data analysis, applying both intention-to-treat (ITT) and complete-case approaches.
Results:
ITT analysis revealed no significant differences between the groups on primary or secondary outcomes. Complete-case analysis, however, showed significant improvements in personal recovery (mean difference 5.81 [95% CI 0.25-11.37]; p=0.040) and reductions in negative self-image, including self-blame (-13.06 [-24.18 to -1.95]; p=0.021) and self-neglect (-14.59 [-28.01 to -1.17]; p=0.033), in the intervention group. Engagement was high, with 91% of the participants using the game for at least 15 minutes. The median total playtime was 55 minutes (IQR: 31, 86), with a median of 13 missions completed (IQR: 8, 18), indicating meaningful interaction over the 15 week period.
Discussion:
While Maze Out did not demonstrate overall efficacy in ITT analyses, improvements in self-image and personal recovery highlight its potential as a feasible and acceptable adjunct to TAU for ED patients. Future studies should explore its long-term effects and utility in specific ED subgroups.
Original languageEnglish
Pages (from-to)1558-1571
Number of pages14
JournalInternational Journal of Eating Disorders
Volume58
Issue number8
Early online date19 May 2025
DOIs
Publication statusPublished - Aug 2025

Bibliographical note

This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in anymedium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.© 2025 The Author(s). International Journal of Eating Disorders published by Wiley Periodicals LLC.

Keywords

  • E-health
  • anorexia nervosa
  • bulimia nervosa
  • coproduction
  • eating disorders
  • play
  • randomized controlled trial
  • serious games

ASJC Scopus subject areas

  • Psychiatry and Mental health

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