Manipulation of the osteoblast response to a Ti-6Al-4V titanium alloy using a high power diode laser

L. Hao, J. Lawrence, L Li

Research output: Contribution to journalConference article

39 Citations (Scopus)

Abstract

To improve the bone integration of titanium-based implants a high power diode laser (HPDL) was used to modify the material for improved osteoblast cell response. The surface properties of un-treated and HPDL treated samples were characterized. Contact angles for the un-treated and the HPDL modified titanium alloy (Ti-6Al-4V) were determined with selected biological liquids by the sessile drop technique. The analysis revealed that the wettability of the Ti-6Al-4V improved after HPDL laser treatment, indicating that better interaction with the biological liquids occurred. Moreover, an in vitro human fetal osteoblast cells (hFOB 1.19) evaluation revealed a more favourable cell response on the HPDL laser treated Ti-6Al-4V alloy than on either un-treated sample or a mechanically roughened sample. It was consequently determined that the HPDL provides more a controllable and effective technique to improve the biocompatibility of bio-metals.

Original languageEnglish
Pages (from-to)602-606
Number of pages5
JournalApplied Surface Science
Volume247
Issue number1-4
Early online date10 Mar 2005
DOIs
Publication statusPublished - 15 Jul 2005
Externally publishedYes
EventEMRS Symposium N 2004 - Strasbourg, France
Duration: 24 May 200428 May 2004

Fingerprint

osteoblasts
Osteoblasts
titanium alloys
Titanium alloys
Semiconductor lasers
manipulators
semiconductor lasers
cells
Lasers
Liquids
biocompatibility
liquids
wettability
Titanium
Biocompatibility
surface properties
bones
Contact angle
lasers
Surface properties

Keywords

  • High power diode laser
  • Osteoblast cell
  • Titanium alloy
  • Wettability

ASJC Scopus subject areas

  • Surfaces, Coatings and Films

Cite this

Manipulation of the osteoblast response to a Ti-6Al-4V titanium alloy using a high power diode laser. / Hao, L.; Lawrence, J.; Li, L.

In: Applied Surface Science, Vol. 247, No. 1-4, 15.07.2005, p. 602-606.

Research output: Contribution to journalConference article

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