Lactone synthesis activity in a site-directed mutant of an extradiol catechol dioxygenase enzyme

Sharon Mendel, Andrew Arndt, Timothy D H Bugg

    Research output: Contribution to journalArticlepeer-review

    3 Citations (Scopus)

    Abstract

    A H115Y site-directed mutant of extradiol catechol dioxygenase MhpB catalyses an intramolecular lactonisation reaction upon its natural substrate.

    Original languageEnglish
    Pages (from-to)666-668
    Number of pages3
    JournalChemical communications (Cambridge, England)
    Issue number5
    DOIs
    Publication statusPublished - 7 Feb 2005

    Keywords

    • Amino Acid Substitution
    • Catalysis
    • Dioxygenases
    • Escherichia coli
    • Lactones
    • Molecular Structure
    • Mutagenesis, Site-Directed
    • Oxygenases
    • Journal Article
    • Research Support, Non-U.S. Gov't

    Fingerprint

    Dive into the research topics of 'Lactone synthesis activity in a site-directed mutant of an extradiol catechol dioxygenase enzyme'. Together they form a unique fingerprint.

    Cite this