Abstract
Original language | English |
---|---|
Pages (from-to) | 39-43 |
Number of pages | 5 |
Journal | Bioscience of Microbiota, Food and Health |
Volume | 37 |
Issue number | 2 |
Early online date | 6 Jan 2018 |
DOIs | |
Publication status | Published - 13 Apr 2018 |
Fingerprint
Bibliographical note
This is an open-access article distributed under the terms of the CreativeCommons Attribution Non-Commercial No Derivatives (by-nc-nd) License.
(CC-BY-NC-ND 4.0: https://creativecommons.org/licenses/by-nc-nd/4.0/)
Cite this
Investigating the transmissibility of tet(W) in bifidobacteria exposed to acid and bile stress. / Polit, Agnieszka; Yang, Huiying; Amund, Daniel.
In: Bioscience of Microbiota, Food and Health, Vol. 37, No. 2, 13.04.2018, p. 39-43.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Investigating the transmissibility of tet(W) in bifidobacteria exposed to acid and bile stress
AU - Polit, Agnieszka
AU - Yang, Huiying
AU - Amund, Daniel
N1 - This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License. (CC-BY-NC-ND 4.0: https://creativecommons.org/licenses/by-nc-nd/4.0/)
PY - 2018/4/13
Y1 - 2018/4/13
N2 - Transfer of antibiotic resistance genes from probiotic bacteria to pathogens poses a safety concern. Orally administered probiotics are exposed to stressful conditions during gastrointestinal transit. In this study, filter mating experiments were performed to investigate the potential role of exposure of Bifidobacterium isolates to acid and bile stress on the transfer of a tetracycline resistance gene, tet(W), to Enterococcus faecalis ATCC 51299. No E. faecalis transconjugants were obtained after mating with either stressed or unstressed Bifidobacterium, thereby suggesting that tet(W) could not be transferred as a result of exposure to gastrointestinal stresses.
AB - Transfer of antibiotic resistance genes from probiotic bacteria to pathogens poses a safety concern. Orally administered probiotics are exposed to stressful conditions during gastrointestinal transit. In this study, filter mating experiments were performed to investigate the potential role of exposure of Bifidobacterium isolates to acid and bile stress on the transfer of a tetracycline resistance gene, tet(W), to Enterococcus faecalis ATCC 51299. No E. faecalis transconjugants were obtained after mating with either stressed or unstressed Bifidobacterium, thereby suggesting that tet(W) could not be transferred as a result of exposure to gastrointestinal stresses.
U2 - 10.12938/bmfh.17-017
DO - 10.12938/bmfh.17-017
M3 - Article
VL - 37
SP - 39
EP - 43
JO - Bioscience of Microbiota, Food and Health
JF - Bioscience of Microbiota, Food and Health
SN - 2186-6953
IS - 2
ER -