Impact of physical activity category on incidence of cardiovascular disease: Results from the 10-year follow-up of the ATTICA Study (2002–2012)

Konstantinos D. Tambalis; Demosthenes B. Panagiotakos; Ekavi N. Georgousopoulou; Duane D. Mellor; Christina Chrysohoou; Georgia Maria Kouli; Dimitrios Tousoulis; Christodoulos Stefanadis; Christos Pitsavos

doi:10.1016/j.ypmed.2016.09.023

Impact of physical activity category on incidence of cardiovascular disease: Results from the 10-year follow-up of the ATTICA Study (2002–2012)

Konstantinos D. Tambalis, Demosthenes B. Panagiotakos, Ekavi N. Georgousopoulou, Duane D. Mellor, Christina Chrysohoou, Georgia Maria Kouli, Dimitrios Tousoulis, Christodoulos Stefanadis, Christos Pitsavos

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

57 Downloads (Pure)

Abstract

The aim of the study was to examine the effects of physical activity (PA) level on 10-year cardiovascular disease (CVD) incidence, taking into consideration several clinical and lifestyle risk factors along with the potential moderating role of gender. An analysis was undertaken on data from the ATTICA prospective cohort study (10-year follow-up, 2002–2012), which followed a Greek adult population (aged 18–89 years). A total n = 317 of fatal and nonfatal CVD events occurred among the 2020 participants. After adjusting for the lifestyle and clinical risk factors as potential confounders, odds ratio (ORs) of CVD risk of individuals who reported being sufficiently active and highly active were decreased by 58% (95% CI: 0.30, 0.58) and 70% (95% CI: 0.15, 0.56), when compared to those who were inactive/insufficiently active, respectively. Men had nearly two-fold increase in risk of CVD (95% CI: 1.62, 2.18) versus women. Stratified analysis by gender, revealed that sufficiently active men, had 52% (95% CI: 0.24, 0.97) reduced risk of CVD incidence when compared to inactive males, while, for women, the role of PA lost significance following adjusting for lifestyle factors. The current data suggests a beneficial effect of even moderate physical activity levels on 10-year incidence of CVD, reinforcing the importance of physically activity, especially for men.

Original language	English
Pages (from-to)	27-32
Number of pages	6
Journal	Preventive Medicine
Volume	93
Early online date	20 Sept 2016
DOIs	https://doi.org/10.1016/j.ypmed.2016.09.023
Publication status	Published - 1 Dec 2016
Externally published	Yes

Bibliographical note

Publisher Statement: NOTICE: this is the author’s version of a work that was accepted for publication in Preventive Medicine. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Preventive Medicine, [93, (2017)] DOI: 10.1016/j.ypmed.2016.09.023

Keywords

CVD
Physical activity level
Prospective study

ASJC Scopus subject areas

Epidemiology
Public Health, Environmental and Occupational Health

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.ypmed.2016.09.023

Post-PrintAccepted author manuscript, 799 KBLicence: CC BY-NC-ND

Cite this

Tambalis, K. D., Panagiotakos, D. B., Georgousopoulou, E. N., Mellor, D. D., Chrysohoou, C., Kouli, G. M., Tousoulis, D., Stefanadis, C., & Pitsavos, C. (2016). Impact of physical activity category on incidence of cardiovascular disease: Results from the 10-year follow-up of the ATTICA Study (2002–2012). Preventive Medicine, 93, 27-32. https://doi.org/10.1016/j.ypmed.2016.09.023

Tambalis, KD, Panagiotakos, DB, Georgousopoulou, EN, Mellor, DD, Chrysohoou, C, Kouli, GM, Tousoulis, D, Stefanadis, C & Pitsavos, C 2016, 'Impact of physical activity category on incidence of cardiovascular disease: Results from the 10-year follow-up of the ATTICA Study (2002–2012)', Preventive Medicine, vol. 93, pp. 27-32. https://doi.org/10.1016/j.ypmed.2016.09.023

@article{1b192c9086a647f5b0f609bc5073f79d,

title = "Impact of physical activity category on incidence of cardiovascular disease: Results from the 10-year follow-up of the ATTICA Study (2002–2012)",

abstract = "The aim of the study was to examine the effects of physical activity (PA) level on 10-year cardiovascular disease (CVD) incidence, taking into consideration several clinical and lifestyle risk factors along with the potential moderating role of gender. An analysis was undertaken on data from the ATTICA prospective cohort study (10-year follow-up, 2002–2012), which followed a Greek adult population (aged 18–89 years). A total n = 317 of fatal and nonfatal CVD events occurred among the 2020 participants. After adjusting for the lifestyle and clinical risk factors as potential confounders, odds ratio (ORs) of CVD risk of individuals who reported being sufficiently active and highly active were decreased by 58% (95% CI: 0.30, 0.58) and 70% (95% CI: 0.15, 0.56), when compared to those who were inactive/insufficiently active, respectively. Men had nearly two-fold increase in risk of CVD (95% CI: 1.62, 2.18) versus women. Stratified analysis by gender, revealed that sufficiently active men, had 52% (95% CI: 0.24, 0.97) reduced risk of CVD incidence when compared to inactive males, while, for women, the role of PA lost significance following adjusting for lifestyle factors. The current data suggests a beneficial effect of even moderate physical activity levels on 10-year incidence of CVD, reinforcing the importance of physically activity, especially for men.",

keywords = "CVD, Physical activity level, Prospective study",

author = "Tambalis, {Konstantinos D.} and Panagiotakos, {Demosthenes B.} and Georgousopoulou, {Ekavi N.} and Mellor, {Duane D.} and Christina Chrysohoou and Kouli, {Georgia Maria} and Dimitrios Tousoulis and Christodoulos Stefanadis and Christos Pitsavos",

note = "Publisher Statement: NOTICE: this is the author{\textquoteright}s version of a work that was accepted for publication in Preventive Medicine. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Preventive Medicine, [93, (2017)] DOI: 10.1016/j.ypmed.2016.09.023 ",

year = "2016",

month = dec,

day = "1",

doi = "10.1016/j.ypmed.2016.09.023",

language = "English",

volume = "93",

pages = "27--32",

journal = "Preventive Medicine",

issn = "0091-7435",

publisher = "Elsevier",

}

TY - JOUR

T1 - Impact of physical activity category on incidence of cardiovascular disease

T2 - Results from the 10-year follow-up of the ATTICA Study (2002–2012)

AU - Tambalis, Konstantinos D.

AU - Panagiotakos, Demosthenes B.

AU - Georgousopoulou, Ekavi N.

AU - Mellor, Duane D.

AU - Chrysohoou, Christina

AU - Kouli, Georgia Maria

AU - Tousoulis, Dimitrios

AU - Stefanadis, Christodoulos

AU - Pitsavos, Christos

N1 - Publisher Statement: NOTICE: this is the author’s version of a work that was accepted for publication in Preventive Medicine. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Preventive Medicine, [93, (2017)] DOI: 10.1016/j.ypmed.2016.09.023

PY - 2016/12/1

Y1 - 2016/12/1

N2 - The aim of the study was to examine the effects of physical activity (PA) level on 10-year cardiovascular disease (CVD) incidence, taking into consideration several clinical and lifestyle risk factors along with the potential moderating role of gender. An analysis was undertaken on data from the ATTICA prospective cohort study (10-year follow-up, 2002–2012), which followed a Greek adult population (aged 18–89 years). A total n = 317 of fatal and nonfatal CVD events occurred among the 2020 participants. After adjusting for the lifestyle and clinical risk factors as potential confounders, odds ratio (ORs) of CVD risk of individuals who reported being sufficiently active and highly active were decreased by 58% (95% CI: 0.30, 0.58) and 70% (95% CI: 0.15, 0.56), when compared to those who were inactive/insufficiently active, respectively. Men had nearly two-fold increase in risk of CVD (95% CI: 1.62, 2.18) versus women. Stratified analysis by gender, revealed that sufficiently active men, had 52% (95% CI: 0.24, 0.97) reduced risk of CVD incidence when compared to inactive males, while, for women, the role of PA lost significance following adjusting for lifestyle factors. The current data suggests a beneficial effect of even moderate physical activity levels on 10-year incidence of CVD, reinforcing the importance of physically activity, especially for men.

AB - The aim of the study was to examine the effects of physical activity (PA) level on 10-year cardiovascular disease (CVD) incidence, taking into consideration several clinical and lifestyle risk factors along with the potential moderating role of gender. An analysis was undertaken on data from the ATTICA prospective cohort study (10-year follow-up, 2002–2012), which followed a Greek adult population (aged 18–89 years). A total n = 317 of fatal and nonfatal CVD events occurred among the 2020 participants. After adjusting for the lifestyle and clinical risk factors as potential confounders, odds ratio (ORs) of CVD risk of individuals who reported being sufficiently active and highly active were decreased by 58% (95% CI: 0.30, 0.58) and 70% (95% CI: 0.15, 0.56), when compared to those who were inactive/insufficiently active, respectively. Men had nearly two-fold increase in risk of CVD (95% CI: 1.62, 2.18) versus women. Stratified analysis by gender, revealed that sufficiently active men, had 52% (95% CI: 0.24, 0.97) reduced risk of CVD incidence when compared to inactive males, while, for women, the role of PA lost significance following adjusting for lifestyle factors. The current data suggests a beneficial effect of even moderate physical activity levels on 10-year incidence of CVD, reinforcing the importance of physically activity, especially for men.

KW - CVD

KW - Physical activity level

KW - Prospective study

U2 - 10.1016/j.ypmed.2016.09.023

DO - 10.1016/j.ypmed.2016.09.023

M3 - Article

AN - SCOPUS:84988476696

SN - 0091-7435

VL - 93

SP - 27

EP - 32

JO - Preventive Medicine

JF - Preventive Medicine

ER -

Impact of physical activity category on incidence of cardiovascular disease: Results from the 10-year follow-up of the ATTICA Study (2002–2012)

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

Fingerprint

Cite this