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Griseofulvin: Generation time and atp changes in the ciliate tetrahymena pyriformis

  • Olivier A. Sparagano
  • University of Reading

Research output: Contribution to journalArticlepeer-review

Abstract

Tetrahymena pyriformis GL populations (20,000 cells/ml and 50,000 cells/ml) were studied at various times after exposure to griseofulvin. Growth rates were significantly different between controls and treated samples 90 min after treatment. ATP levels decreased in treated samples after 45 min. No differencies were observed between controls and populations treated with acetone used to dissolve griseofulvin.

Original languageEnglish
Pages (from-to)897-901
Number of pages5
JournalLife Sciences
Volume57
Issue number9
DOIs
Publication statusPublished - 21 Jul 1995
Externally publishedYes

Keywords

  • antifungal drug
  • ATP
  • ciliate
  • Tetrahymena pyriformis

ASJC Scopus subject areas

  • General Biochemistry,Genetics and Molecular Biology
  • Pharmacology, Toxicology and Pharmaceutics(all)

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