Functional Magnetic Resonance Imaging: An Overview of Technical Advances and Clinical Applications

Lumeng Zhang, Xinhong Wang, Haipeng Liu

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


Functional magnetic resonance imaging (fMRI), with its unique advantages of non-invasiveness, relatively balanced spatial and temporal resolution, repeatability, and whole brain imaging, has brought methodological breakthroughs to neuroscience and neurological clinical practice. By measuring blood oxygen-dependent signals, fMRI can reveal brain activity in task execution, sensory stimulation, and emotional regulation. By comparing the brain functional activity between patients and normal controls, fMRI can detect the abnormal brain regions associated with mental illness. During the rehabilitation of stroke, traumatic brain injury, and neurodegenerative diseases, fMRI enables the evaluation of brain function recovery and guides personalized training. This chapter introduces the working principle of fMRI and summarizes the state of the art, providing references for clinicians, researchers in neuroscience, and biomedical engineers.
Original languageEnglish
Title of host publicationAI-Driven Innovations in Digital Healthcare: Emerging Trends, Challenges, and Applications
EditorsAlex Khang
PublisherIGI Global
Number of pages21
ISBN (Electronic)9798369332191
ISBN (Print)9798369332184
Publication statusPublished - 5 Jan 2024

Publication series

NameAI-Driven Innovations in Digital Healthcare
PublisherIGI Global
ISSN (Print)2475-6628


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