Abstract
This paper presents a new control methodology for high throughput optoelectronic/optogenetic prostheses. Optogenetic prostheses use a gene therapy method to photosensitize neurons, for which the most efficient stimulation is short pulses of just enough high intensity light. We have previously demonstrated that stimulation can be achieved with combined CMOS-Nitride micro-photonic systems. We have now explored operating schemes to provide accurate short pulses of high radiance light in an intensity modulation scheme for the purpose of retinal prosthesis. We have shown that by utilizing the sparse nature of retinal code, it is possible to have an adaptive system which minimizes information transfer compared to raster or purely asynchronous bit serial modes. We are thus being able to provide more dynamic and thus intensity accuracy. We have implemented our schemes on an FPGA to measure relative modes.
Original language | English |
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Title of host publication | 2013 IEEE Biomedical Circuits and Systems Conference (BioCAS) |
Publisher | IEEE |
Pages | 190-193 |
Number of pages | 4 |
ISBN (Electronic) | 978-1-4799-1471-5, 978-1-4799-1470-8 |
ISBN (Print) | 978-1-4799-1469-2 |
DOIs | |
Publication status | Published - 2013 |
Event | 2013 IEEE Biomedical Circuits and Systems Conference - Rotterdam, Netherlands Duration: 31 Oct 2013 → 2 Nov 2013 |
Conference
Conference | 2013 IEEE Biomedical Circuits and Systems Conference |
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Abbreviated title | BioCAS |
Country/Territory | Netherlands |
City | Rotterdam |
Period | 31/10/13 → 2/11/13 |
Keywords
- Prosthetics
- Retina
- Field programmable gate arrays
- Registers
- Visualization
- Neurons
- Clocks
- prosthetics
- bioelectric potentials
- bio-optics
- CMOS integrated circuits
- encoding
- eye
- field programmable gate arrays
- gene therapy
- intensity modulation
- micro-optics
- neurophysiology
- optoelectronic devices
- relative mode measurement
- FPGA design
- pulse encoder
- optoelectronic neural stimulation
- recording array
- control methodology
- high throughput optoelectronic-optogenetic prosthesis
- gene therapy method
- neuron photosensitization
- short pulse stimulation
- high intensity light
- CMOS-nitride microphotonic system
- high radiance light
- intensity modulation scheme
- retinal prosthesis
- sparse retinal code
- adaptive system
- information transfer minimization
- raster mode
- purely asynchronous bit serial mode
- intensity accuracy
- optoelectronics
- optogenetic
- visual prosthesis
- neural prosthesis
- bionics
- neurobionics
- biomedical
- FPGA
- Controller