Evaluation of antimalarial, free-radical-scavenging and insecticidal activities of Artemisia scoparia and A. Spicigera, Asteraceae

F.H. Afshar, A. Delazar, Omar Janneh, H. Nazemiyeh, A. Pasdaran, L. Nahar, S.D. Sarker

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    Abstract

    Artemisia species (Asteraceae), widespread throughout the world, are a group of important medicinal plants. The extracts of two medicinal plants of this genus, Artemisia scoparia Waldst. & Kit. and A. spicigera C. Koch, were evaluated for potential antimalarial, free-radical-scavenging and insecticidal properties, using the heme biocrystallisation and inhibition assay, the DPPH assay and the contact toxicity bioassay using the pest Tribolium castaneum, respectively. The methanol extracts of both species showed strong free-radical-scavenging activity and the RC50 values were 0.0317 and 0.0458 mg/mL, respectively, for A. scoparia and A. spicigera. The dichloromethane extracts of both species displayed a moderate level of potential antimalarial activity providing IC50 at 0.778 and 0.999 mg/mL for A. scoparia and A. spicigera, respectively. Both species of Artemisia showed insecticidal properties. However, A. spicigera was more effective than A. scoparia.
    Original languageEnglish
    Pages (from-to)986-990
    JournalRevista Brasileira de Farmacognosia
    Volume21
    Issue number6
    DOIs
    Publication statusPublished - 2011

    Bibliographical note

    This publication is made available under a creative-commons attribution-noncommercial licence. You are free to copy, distribute, transmit and adapt the work for non-commercial purposes providing appropriate attribution is given. Full details of the licence are available from http://creativecommons.org/licenses/by-nc/3.0/

    Keywords

    • Artemisia scoparia
    • Artemisia spicigera
    • Asteraceae
    • DPPH
    • antimalaria
    • insecticide

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