Efficacité des vaccins antigrippes chez la personne âgée

P. O. Lang; S. Govind; R. Aspinall

doi:10.1016/j.npg.2012.03.001

Efficacité des vaccins antigrippes chez la personne âgée

Translated title of the contribution: Effectiveness of influenza vaccines in the elderly

P. O. Lang, S. Govind, R. Aspinall

Research output: Contribution to journal › Review article › peer-review

2 Citations (Scopus)

Abstract

Annual vaccination is considered to be the cornerstone for preventing seasonal influenza infections. Trivalent inactivated influenza virus vaccines (TIV) are believed to be not only effective but also cost-effective. Although they effectively prevent 70 to 90% of infections in adults, the measurement of their efficacy in the older adult population appears to be less precise and is still a controversial subject. From recent meta-analyses, this review will aim to examine how effective current TIV really are in the older adult, and analyze the most important factors that have biased the benefits measured in this population. Finally, this review concludes with practical recommendations and possible strategies to improve the assessment of the true benefits of influenza vaccines in the aged population.

Translated title of the contribution	Effectiveness of influenza vaccines in the elderly
Original language	French
Pages (from-to)	121-130
Number of pages	10
Journal	NPG Neurologie - Psychiatrie - Geriatrie
Volume	12
Issue number	69
Early online date	27 Apr 2012
DOIs	https://doi.org/10.1016/j.npg.2012.03.001
Publication status	Published - Jun 2012
Externally published	Yes

Keywords

Hemagglutinin activity inhibition
Immunosenescence
Influenza vaccine effectiveness
Influenza virus infection
Older adults

ASJC Scopus subject areas

Clinical Neurology
Geriatrics and Gerontology
Psychiatry and Mental health

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.npg.2012.03.001

Cite this

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title = "Efficacit{\'e} des vaccins antigrippes chez la personne {\^a}g{\'e}e",

abstract = "Annual vaccination is considered to be the cornerstone for preventing seasonal influenza infections. Trivalent inactivated influenza virus vaccines (TIV) are believed to be not only effective but also cost-effective. Although they effectively prevent 70 to 90% of infections in adults, the measurement of their efficacy in the older adult population appears to be less precise and is still a controversial subject. From recent meta-analyses, this review will aim to examine how effective current TIV really are in the older adult, and analyze the most important factors that have biased the benefits measured in this population. Finally, this review concludes with practical recommendations and possible strategies to improve the assessment of the true benefits of influenza vaccines in the aged population.",

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author = "Lang, {P. O.} and S. Govind and R. Aspinall",

year = "2012",

month = jun,

doi = "10.1016/j.npg.2012.03.001",

language = "French",

volume = "12",

pages = "121--130",

journal = "NPG Neurologie - Psychiatrie - Geriatrie",

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publisher = "Elsevier",

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T1 - Efficacité des vaccins antigrippes chez la personne âgée

AU - Lang, P. O.

AU - Govind, S.

AU - Aspinall, R.

PY - 2012/6

Y1 - 2012/6

N2 - Annual vaccination is considered to be the cornerstone for preventing seasonal influenza infections. Trivalent inactivated influenza virus vaccines (TIV) are believed to be not only effective but also cost-effective. Although they effectively prevent 70 to 90% of infections in adults, the measurement of their efficacy in the older adult population appears to be less precise and is still a controversial subject. From recent meta-analyses, this review will aim to examine how effective current TIV really are in the older adult, and analyze the most important factors that have biased the benefits measured in this population. Finally, this review concludes with practical recommendations and possible strategies to improve the assessment of the true benefits of influenza vaccines in the aged population.

AB - Annual vaccination is considered to be the cornerstone for preventing seasonal influenza infections. Trivalent inactivated influenza virus vaccines (TIV) are believed to be not only effective but also cost-effective. Although they effectively prevent 70 to 90% of infections in adults, the measurement of their efficacy in the older adult population appears to be less precise and is still a controversial subject. From recent meta-analyses, this review will aim to examine how effective current TIV really are in the older adult, and analyze the most important factors that have biased the benefits measured in this population. Finally, this review concludes with practical recommendations and possible strategies to improve the assessment of the true benefits of influenza vaccines in the aged population.

KW - Hemagglutinin activity inhibition

KW - Immunosenescence

KW - Influenza vaccine effectiveness

KW - Influenza virus infection

KW - Older adults

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U2 - 10.1016/j.npg.2012.03.001

DO - 10.1016/j.npg.2012.03.001

M3 - Review article

AN - SCOPUS:84861940252

SN - 1627-4830

VL - 12

SP - 121

EP - 130

JO - NPG Neurologie - Psychiatrie - Geriatrie

JF - NPG Neurologie - Psychiatrie - Geriatrie

IS - 69

ER -

Efficacité des vaccins antigrippes chez la personne âgée

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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