Abstract
Axenic cultures of Tetrahymena pyriformis GL populations were exposed to 0.40 μg/mL of tetra methylthiuram disulphide (TMTD). Doubling times and ATP, ADP and AMP levels were followed on control and treated populations at various cell densities during the exponential growth phase. For the control populations, the average generation time was 171.9 min and ATP levels were 2-8 x 10-14 mol/cell. For the treated populations, growth was reduced and the populations with the highest densities were more sensitive than populations treated with TMTD at the early stage of the exponential growth phase. For treated populations, ATP and ADP concentrations showed significant differences compared to the control populations. Mechanisms compensating the action of the TMTD have been observed with treated populations at 25,000 cells/mL density. Unfortunately AMP levels were unstable within control populations showing no differences with those from treated populations.
Original language | English |
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Pages (from-to) | 409-413 |
Number of pages | 5 |
Journal | Environmental Toxicology |
Volume | 14 |
Issue number | 4 |
DOIs | |
Publication status | Published - 9 Sept 1999 |
Externally published | Yes |
Keywords
- ATP
- Fungicide
- Protist
- Tetrahymena pyriformis
- Toxicology
ASJC Scopus subject areas
- Toxicology
- Management, Monitoring, Policy and Law
- Health, Toxicology and Mutagenesis