Effectiveness of influenza vaccines in the elderly

P. O. Lang, S. Govind, R. Aspinall

Research output: Contribution to journalReview article

2 Citations (Scopus)

Abstract

Annual vaccination is considered to be the cornerstone for preventing seasonal influenza infections. Trivalent inactivated influenza virus vaccines (TIV) are believed to be not only effective but also cost-effective. Although they effectively prevent 70 to 90% of infections in adults, the measurement of their efficacy in the older adult population appears to be less precise and is still a controversial subject. From recent meta-analyses, this review will aim to examine how effective current TIV really are in the older adult, and analyze the most important factors that have biased the benefits measured in this population. Finally, this review concludes with practical recommendations and possible strategies to improve the assessment of the true benefits of influenza vaccines in the aged population.

Translated title of the contributionEffectiveness of influenza vaccines in the elderly
Original languageFrench
Pages (from-to)121-130
Number of pages10
JournalNPG Neurologie - Psychiatrie - Geriatrie
Volume12
Issue number69
Early online date27 Apr 2012
DOIs
Publication statusPublished - Jun 2012
Externally publishedYes

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Keywords

  • Hemagglutinin activity inhibition
  • Immunosenescence
  • Influenza vaccine effectiveness
  • Influenza virus infection
  • Older adults

ASJC Scopus subject areas

  • Clinical Neurology
  • Geriatrics and Gerontology
  • Psychiatry and Mental health

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