Effect of phacoemulsification on trabeculectomy function

Dan Q Nguyen, Nuwan Niyadurupola, Robyn J Tapp, Rachael A O'Connell, Michael A Coote, Jonathan G Crowston

Research output: Contribution to journalArticlepeer-review

28 Citations (Scopus)


BACKGROUND: To evaluate the effect of phacoemulsification on trabeculectomy function.

DESIGN: Retrospective case-control study.

PARTICIPANTS: Forty-eight patients who underwent trabeculectomy surgery and had at least 2 years of follow up.

METHODS: Patients were classified into two groups: patients who had phacoemulsification subsequent to trabeculectomy (Trab_phaco, n = 18) and patients who were pseudophakic for greater than 6 months preceding their trabeculectomy (Phaco_trab, n = 30). Groups were matched for length of follow up of 2 years from time of trabeculectomy.

MAIN OUTCOME MEASURES: The primary outcome measures were target intraocular pressure of criteria A, ≤12 mmHg; B, ≤15 mmHg; C, ≤18 mmHg with or without additional topical treatment. A separate measure for bleb function failure was also used; with failure defined as the need for additional topical antiglaucoma therapy or surgical intervention to achieve control of intraocular pressure.

RESULTS: There was no significant difference in achieving each intraocular pressure criterion between groups (12 months, P = 1.0; 24 months, P = 0.330). In the first 12 months, significantly more trabeculectomies in the Trab_phaco group failed, requiring additional intervention to control the IOP (39%) compared with the Phaco_trab (10%) group (P = 0.028). Although this trend continued at 24 months, there were no significant differences in failure rates (P = 0.522).

CONCLUSIONS: Phacoemulsification performed after trabeculectomy significantly increased rates of bleb failure in the following 12 months but not at 24 months.

Original languageEnglish
Pages (from-to)433-439
Number of pages7
JournalClinical & experimental ophthalmology
Issue number5
Early online date17 Dec 2013
Publication statusPublished - Jul 2014
Externally publishedYes


  • Aged
  • Aged, 80 and over
  • Case-Control Studies
  • Female
  • Glaucoma, Angle-Closure/physiopathology
  • Glaucoma, Open-Angle/physiopathology
  • Humans
  • Intraocular Pressure/physiology
  • Lens Implantation, Intraocular
  • Male
  • Phacoemulsification
  • Pseudophakia/physiopathology
  • Retrospective Studies
  • Tonometry, Ocular
  • Trabecular Meshwork/physiopathology
  • Trabeculectomy
  • Visual Acuity


Dive into the research topics of 'Effect of phacoemulsification on trabeculectomy function'. Together they form a unique fingerprint.

Cite this