Abstract
Background
Systematic reviews of early rehabilitation within intensive care units have highlighted the need for robust multi-centre randomised controlled trials with longer term follow up. This trial aims to explore the feasibility of earlier and enhanced rehabilitation for patients mechanically ventilated for ≥ 5 days and to assess the impact on possible long term outcome measures for use in a definitive trial.
Methods
Patients admitted to a large UK based intensive care unit and invasively ventilated for ≥ 5 days were randomised to the rehabilitation intervention or standard care on a 1:1 basis, stratified by age and SOFA score. The rehabilitation intervention involved a structured programme, with progression along a functionally based mobility protocol according to set safety criteria.
Results
103 out of 128 eligible patients were recruited into the trial, achieving an initial recruitment rate of 80%. Patients in the intervention arm mobilized significantly earlier (8 days vs 10 days, p = 0.035), at a more acute phase of illness (SOFA 6 vs 4, p < 0.05) and reached a higher level of mobility at the point of critical care discharge (MMS 7 vs 5, p < 0.01).
Conclusion
We have demonstrated the feasibility of introducing a structured programme of rehabilitation for patients admitted to critical care.
Original language | English |
---|---|
Pages (from-to) | 407-412 |
Number of pages | 6 |
Journal | Journal of Critical Care |
Volume | 44 |
DOIs | |
Publication status | Published - Apr 2018 |
Externally published | Yes |
Bibliographical note
This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Contents lists available at Science Direct Journal of Critical Care journal homepage:www.jccjournal.orgKeywords
- Rehabilitation
- Critical care
- Physiotherapy
- Exercise
- ICU