Abstract
Anxiety disorders are heightened in specific genetic syndromes in comparison to intellectual disability of heterogeneous etiology. In this study we described and contrasted anxiety symptomatology in fragile X (FXS), Cornelia de Lange (CdLS) and Rubinstein-Taybi syndromes (RTS), and compared the symptomatology to normative data for typically-developing children and children diagnosed with an anxiety disorder. Scores did not differ between children diagnosed with an anxiety disorder and: a) participants with FXS on social phobia, panic/agoraphobia, physical injury fears, and obsessive-compulsive subscales, b) participants with CdLS on separation anxiety, generalized anxiety, panic/agoraphobia, physical injury fears and obsessive-compulsive subscales, and c) participants with RTS on panic/agoraphobia and obsessive-compulsive subscales. The results highlight divergent profiles of anxiety symptomatology between these groups.
| Original language | English |
|---|---|
| Pages (from-to) | 3728-3740 |
| Number of pages | 13 |
| Journal | Journal of Autism and Developmental Disorders |
| Volume | 47 |
| Issue number | 12 |
| Early online date | 31 Jan 2017 |
| DOIs | |
| Publication status | Published - Dec 2017 |
Bibliographical note
This article has been accepted for publication in the Journal of Autism and Developmental Disorders.This article is distributed under the terms of the
Creative Commons Attribution 4.0 International License (http://
creativecommons.org/licenses/by/4.0/), which permits unrestricted
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Keywords
- Anxiety
- genetic syndromes
- fragile X syndrome
- Cornelia de Lange syndrome
- Rubinstein-Taybi syndrome
- intellectual disability