Dietary intakes and food sources of phytoestrogens in the European Prospective Investigation into Cancer and Nutrition (EPIC) 24-hour dietary recall cohort

R. Zamora-Ros; V. Knaze; L. Luján-Barroso; G. G C Kuhnle; A. A. Mulligan; M. Touillaud; N. Slimani; I. Romieu; N. Powell; R. Tumino; P. H M Peeters; M. S. De Magistris; F. Ricceri; E. Sonestedt; I. Drake; A. Hjartker; G. Skie; T. Mouw; P. A. Wark; D. Romaguera; H. B. Bueno-De-Mesquita; M. Ros; E. Molina; S. Sieri; J. R. Quirós; J. M. Huerta; A. Tjønneland; J. Halkjær; G. Masala; B. Teucher; R. Kaas; R. C. Travis; V. Dilis; V. Benetou; A. Trichopoulou; P. Amiano; E. Ardanaz; H. Boeing; J. Förster; F. Clavel-Chapelon; G. Fagherazzi; F. Perquier; G. Johansson; I. Johansson; A. Cassidy; K. Overvad; C. A. González

doi:10.1038/ejcn.2012.36

Dietary intakes and food sources of phytoestrogens in the European Prospective Investigation into Cancer and Nutrition (EPIC) 24-hour dietary recall cohort

R. Zamora-Ros
, V. Knaze
, L. Luján-Barroso
, G. G C Kuhnle
, A. A. Mulligan
, M. Touillaud
, N. Slimani
, I. Romieu
, N. Powell
, R. Tumino
, P. H M Peeters
, M. S. De Magistris
, F. Ricceri
, E. Sonestedt
, I. Drake
, A. Hjartker
, G. Skie
, T. Mouw
, P. A. Wark
, D. Romaguera

H. B. Bueno-De-Mesquita, M. Ros, E. Molina, S. Sieri, J. R. Quirós, J. M. Huerta, A. Tjønneland, J. Halkjær, G. Masala, B. Teucher, R. Kaas, R. C. Travis, V. Dilis, V. Benetou, A. Trichopoulou, P. Amiano, E. Ardanaz, H. Boeing, J. Förster, F. Clavel-Chapelon, G. Fagherazzi, F. Perquier, G. Johansson, I. Johansson, A. Cassidy, K. Overvad, C. A. González

Catalan Institute of Oncology
University of Reading
University of Cambridge
International Agency for Research on Cancer
Azienda Sanitaria Provinciale di Ragusa (ASP Ragusa)
Federico II University
HuGeF Foundation
Lund University
University of Oslo
University of Tromsø
University of Utrecht
Radboud University Medical Center
CIBER de Epidemiología y Salud Pública (CIBERESP)
Fondazione IRCCS Istituto Nazionale dei Tumori
Public Health and Health Planning Directorate
Murcia Regional Health Authority
Institute of Cancer Epidemiology - Denmark
Institute for the Study and Prevention of Cancer
German Cancer Research Center (DKFZ)
University of Oxford
Hellenic Health Foundation
National and Kapodistrian University of Athens
Institute Investigation BioDonostia
Navarra Public Health Institute
German Institute of Human Nutrition
Université Paris-Sud
Umeå University
University of East Anglia
Aarhus University
National Institute for Public Health and the Environment
Andalusian School of Public Health
Institut Gustave Roussy
Imperial College London

Research output: Contribution to journal › Article › peer-review

118 Citations (Scopus)

Abstract

BACKGROUND/OBJECTIVES:Phytoestrogens are estradiol-like natural compounds found in plants that have been associated with protective effects against chronic diseases, including some cancers, cardiovascular diseases and osteoporosis. The purpose of this study was to estimate the dietary intake of phytoestrogens, identify their food sources and their association with lifestyle factors in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort.

SUBJECTS/METHODS:Single 24-hour dietary recalls were collected from 36 037 individuals from 10 European countries, aged 35-74 years using a standardized computerized interview programe (EPIC-Soft). An ad hoc food composition database on phytoestrogens (isoflavones, lignans, coumestans, enterolignans and equol) was compiled using data from available databases, in order to obtain and describe phytoestrogen intakes and their food sources across 27 redefined EPIC centres.

RESULTS:Mean total phytoestrogen intake was the highest in the UK health-conscious group (24.9 mg/day in men and 21.1 mg/day in women) whereas lowest in Greece (1.3 mg/day) in men and Spain-Granada (1.0 mg/day) in women. Northern European countries had higher intakes than southern countries. The main phytoestrogen contributors were isoflavones in both UK centres and lignans in the other EPIC cohorts. Age, body mass index, educational level, smoking status and physical activity were related to increased intakes of lignans, enterolignans and equol, but not to total phytoestrogen, isoflavone or coumestan intakes. In the UK cohorts, the major food sources of phytoestrogens were soy products. In the other EPIC cohorts the dietary sources were more distributed, among fruits, vegetables, soy products, cereal products, non-alcoholic and alcoholic beverages.

CONCLUSIONS:There was a high variability in the dietary intake of total and phytoestrogen subclasses and their food sources across European regions.

Original language	English
Pages (from-to)	932-941
Number of pages	10
Journal	European Journal of Clinical Nutrition
Volume	66
Issue number	8
DOIs	https://doi.org/10.1038/ejcn.2012.36
Publication status	Published - 18 Aug 2012

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

EPIC-Europe
food sources
intake
phytoestrogens

ASJC Scopus subject areas

Medicine (miscellaneous)
Nutrition and Dietetics

Access to Document

10.1038/ejcn.2012.36

Cite this

Zamora-Ros, R., Knaze, V., Luján-Barroso, L., Kuhnle, G. G. C., Mulligan, A. A., Touillaud, M., Slimani, N., Romieu, I., Powell, N., Tumino, R., Peeters, P. H. M., De Magistris, M. S., Ricceri, F., Sonestedt, E., Drake, I., Hjartker, A., Skie, G., Mouw, T., Wark, P. A., ... González, C. A. (2012). Dietary intakes and food sources of phytoestrogens in the European Prospective Investigation into Cancer and Nutrition (EPIC) 24-hour dietary recall cohort. European Journal of Clinical Nutrition, 66(8), 932-941. https://doi.org/10.1038/ejcn.2012.36

Zamora-Ros, R, Knaze, V, Luján-Barroso, L, Kuhnle, GGC, Mulligan, AA, Touillaud, M, Slimani, N, Romieu, I, Powell, N, Tumino, R, Peeters, PHM, De Magistris, MS, Ricceri, F, Sonestedt, E, Drake, I, Hjartker, A, Skie, G, Mouw, T, Wark, PA, Romaguera, D, Bueno-De-Mesquita, HB, Ros, M, Molina, E, Sieri, S, Quirós, JR, Huerta, JM, Tjønneland, A, Halkjær, J, Masala, G, Teucher, B, Kaas, R, Travis, RC, Dilis, V, Benetou, V, Trichopoulou, A, Amiano, P, Ardanaz, E, Boeing, H, Förster, J, Clavel-Chapelon, F, Fagherazzi, G, Perquier, F, Johansson, G, Johansson, I, Cassidy, A, Overvad, K & González, CA 2012, 'Dietary intakes and food sources of phytoestrogens in the European Prospective Investigation into Cancer and Nutrition (EPIC) 24-hour dietary recall cohort', European Journal of Clinical Nutrition, vol. 66, no. 8, pp. 932-941. https://doi.org/10.1038/ejcn.2012.36

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title = "Dietary intakes and food sources of phytoestrogens in the European Prospective Investigation into Cancer and Nutrition (EPIC) 24-hour dietary recall cohort",

abstract = "BACKGROUND/OBJECTIVES:Phytoestrogens are estradiol-like natural compounds found in plants that have been associated with protective effects against chronic diseases, including some cancers, cardiovascular diseases and osteoporosis. The purpose of this study was to estimate the dietary intake of phytoestrogens, identify their food sources and their association with lifestyle factors in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort.SUBJECTS/METHODS:Single 24-hour dietary recalls were collected from 36 037 individuals from 10 European countries, aged 35-74 years using a standardized computerized interview programe (EPIC-Soft). An ad hoc food composition database on phytoestrogens (isoflavones, lignans, coumestans, enterolignans and equol) was compiled using data from available databases, in order to obtain and describe phytoestrogen intakes and their food sources across 27 redefined EPIC centres.RESULTS:Mean total phytoestrogen intake was the highest in the UK health-conscious group (24.9 mg/day in men and 21.1 mg/day in women) whereas lowest in Greece (1.3 mg/day) in men and Spain-Granada (1.0 mg/day) in women. Northern European countries had higher intakes than southern countries. The main phytoestrogen contributors were isoflavones in both UK centres and lignans in the other EPIC cohorts. Age, body mass index, educational level, smoking status and physical activity were related to increased intakes of lignans, enterolignans and equol, but not to total phytoestrogen, isoflavone or coumestan intakes. In the UK cohorts, the major food sources of phytoestrogens were soy products. In the other EPIC cohorts the dietary sources were more distributed, among fruits, vegetables, soy products, cereal products, non-alcoholic and alcoholic beverages.CONCLUSIONS:There was a high variability in the dietary intake of total and phytoestrogen subclasses and their food sources across European regions.",

keywords = "EPIC-Europe, food sources, intake, phytoestrogens",

author = "R. Zamora-Ros and V. Knaze and L. Luj{\'a}n-Barroso and Kuhnle, \{G. G C\} and Mulligan, \{A. A.\} and M. Touillaud and N. Slimani and I. Romieu and N. Powell and R. Tumino and Peeters, \{P. H M\} and \{De Magistris\}, \{M. S.\} and F. Ricceri and E. Sonestedt and I. Drake and A. Hjartker and G. Skie and T. Mouw and Wark, \{P. A.\} and D. Romaguera and Bueno-De-Mesquita, \{H. B.\} and M. Ros and E. Molina and S. Sieri and Quir{\'o}s, \{J. R.\} and Huerta, \{J. M.\} and A. Tj{\o}nneland and J. Halkj{\ae}r and G. Masala and B. Teucher and R. Kaas and Travis, \{R. C.\} and V. Dilis and V. Benetou and A. Trichopoulou and P. Amiano and E. Ardanaz and H. Boeing and J. F{\"o}rster and F. Clavel-Chapelon and G. Fagherazzi and F. Perquier and G. Johansson and I. Johansson and A. Cassidy and K. Overvad and Gonz{\'a}lez, \{C. A.\}",

year = "2012",

month = aug,

day = "18",

doi = "10.1038/ejcn.2012.36",

language = "English",

volume = "66",

pages = "932--941",

journal = "European Journal of Clinical Nutrition",

issn = "0954-3007",

publisher = "Dr. Dietrich Steinkopff Verlag GmbH and Co. KG",

number = "8",

}

TY - JOUR

T1 - Dietary intakes and food sources of phytoestrogens in the European Prospective Investigation into Cancer and Nutrition (EPIC) 24-hour dietary recall cohort

AU - Zamora-Ros, R.

AU - Knaze, V.

AU - Luján-Barroso, L.

AU - Kuhnle, G. G C

AU - Mulligan, A. A.

AU - Touillaud, M.

AU - Slimani, N.

AU - Romieu, I.

AU - Powell, N.

AU - Tumino, R.

AU - Peeters, P. H M

AU - De Magistris, M. S.

AU - Ricceri, F.

AU - Sonestedt, E.

AU - Drake, I.

AU - Hjartker, A.

AU - Skie, G.

AU - Mouw, T.

AU - Wark, P. A.

AU - Romaguera, D.

AU - Bueno-De-Mesquita, H. B.

AU - Ros, M.

AU - Molina, E.

AU - Sieri, S.

AU - Quirós, J. R.

AU - Huerta, J. M.

AU - Tjønneland, A.

AU - Halkjær, J.

AU - Masala, G.

AU - Teucher, B.

AU - Kaas, R.

AU - Travis, R. C.

AU - Dilis, V.

AU - Benetou, V.

AU - Trichopoulou, A.

AU - Amiano, P.

AU - Ardanaz, E.

AU - Boeing, H.

AU - Förster, J.

AU - Clavel-Chapelon, F.

AU - Fagherazzi, G.

AU - Perquier, F.

AU - Johansson, G.

AU - Johansson, I.

AU - Cassidy, A.

AU - Overvad, K.

AU - González, C. A.

PY - 2012/8/18

Y1 - 2012/8/18

N2 - BACKGROUND/OBJECTIVES:Phytoestrogens are estradiol-like natural compounds found in plants that have been associated with protective effects against chronic diseases, including some cancers, cardiovascular diseases and osteoporosis. The purpose of this study was to estimate the dietary intake of phytoestrogens, identify their food sources and their association with lifestyle factors in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort.SUBJECTS/METHODS:Single 24-hour dietary recalls were collected from 36 037 individuals from 10 European countries, aged 35-74 years using a standardized computerized interview programe (EPIC-Soft). An ad hoc food composition database on phytoestrogens (isoflavones, lignans, coumestans, enterolignans and equol) was compiled using data from available databases, in order to obtain and describe phytoestrogen intakes and their food sources across 27 redefined EPIC centres.RESULTS:Mean total phytoestrogen intake was the highest in the UK health-conscious group (24.9 mg/day in men and 21.1 mg/day in women) whereas lowest in Greece (1.3 mg/day) in men and Spain-Granada (1.0 mg/day) in women. Northern European countries had higher intakes than southern countries. The main phytoestrogen contributors were isoflavones in both UK centres and lignans in the other EPIC cohorts. Age, body mass index, educational level, smoking status and physical activity were related to increased intakes of lignans, enterolignans and equol, but not to total phytoestrogen, isoflavone or coumestan intakes. In the UK cohorts, the major food sources of phytoestrogens were soy products. In the other EPIC cohorts the dietary sources were more distributed, among fruits, vegetables, soy products, cereal products, non-alcoholic and alcoholic beverages.CONCLUSIONS:There was a high variability in the dietary intake of total and phytoestrogen subclasses and their food sources across European regions.

AB - BACKGROUND/OBJECTIVES:Phytoestrogens are estradiol-like natural compounds found in plants that have been associated with protective effects against chronic diseases, including some cancers, cardiovascular diseases and osteoporosis. The purpose of this study was to estimate the dietary intake of phytoestrogens, identify their food sources and their association with lifestyle factors in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort.SUBJECTS/METHODS:Single 24-hour dietary recalls were collected from 36 037 individuals from 10 European countries, aged 35-74 years using a standardized computerized interview programe (EPIC-Soft). An ad hoc food composition database on phytoestrogens (isoflavones, lignans, coumestans, enterolignans and equol) was compiled using data from available databases, in order to obtain and describe phytoestrogen intakes and their food sources across 27 redefined EPIC centres.RESULTS:Mean total phytoestrogen intake was the highest in the UK health-conscious group (24.9 mg/day in men and 21.1 mg/day in women) whereas lowest in Greece (1.3 mg/day) in men and Spain-Granada (1.0 mg/day) in women. Northern European countries had higher intakes than southern countries. The main phytoestrogen contributors were isoflavones in both UK centres and lignans in the other EPIC cohorts. Age, body mass index, educational level, smoking status and physical activity were related to increased intakes of lignans, enterolignans and equol, but not to total phytoestrogen, isoflavone or coumestan intakes. In the UK cohorts, the major food sources of phytoestrogens were soy products. In the other EPIC cohorts the dietary sources were more distributed, among fruits, vegetables, soy products, cereal products, non-alcoholic and alcoholic beverages.CONCLUSIONS:There was a high variability in the dietary intake of total and phytoestrogen subclasses and their food sources across European regions.

KW - EPIC-Europe

KW - food sources

KW - intake

KW - phytoestrogens

U2 - 10.1038/ejcn.2012.36

DO - 10.1038/ejcn.2012.36

M3 - Article

C2 - 22510793

AN - SCOPUS:84864840193

SN - 0954-3007

VL - 66

SP - 932

EP - 941

JO - European Journal of Clinical Nutrition

JF - European Journal of Clinical Nutrition

IS - 8

ER -

Dietary intakes and food sources of phytoestrogens in the European Prospective Investigation into Cancer and Nutrition (EPIC) 24-hour dietary recall cohort

Abstract

UN SDGs

Keywords

ASJC Scopus subject areas

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