OBJECTIVE: Dialkylcarbomoyl chloride (DACC)-coated dressings (Leukomed Sorbact and Cutimed Sorbact) irreversibly bind bacteria at the wound surface that are then removed when the dressing is changed. They are a recent addition to the wound care professional's armamentarium and have been used in a variety of acute and chronic wounds. This systematic review aims to assess the evidence supporting the use of DACC-coated dressings in the clinical environment.
METHOD: We included all reports of the clinical use of DACC-coated dressings in relation to wound infection. Medline, Embase, CENTRAL and CINAHL databases were searched to September 2016 for studies evaluating the role of DACC-coated dressings in preventing or managing wound infections.
RESULTS: We identified 17 studies with a total of 3408 patients which were included in this review. The DACC-coating was suggested to reduce postoperative surgical site infection rates and result in chronic wounds that subjectively looked cleaner and had less bacterial load on microbiological assessments.
CONCLUSION: Existing evidence for DACC-coated dressings in managing chronic wounds or as a surgical site infection (SSI) prophylaxis is limited but encouraging with evidence in support of DACC-coated dressings preventing and treating infection without adverse effects.
Bibliographical noteThis document is the Accepted Manuscript version of a Published Work that appeared in final form in Journal of Wound Care, copyright © MA Healthcare, after peer review and technical editing by the publisher. To access the final edited and published work see https://dx.doi.org/10.12968/jowc.2017.26.3.107
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- Ambulatory Care/methods
- Anti-Bacterial Agents/administration & dosage
- Anti-Infective Agents/administration & dosage
- Hydrocarbons, Chlorinated/administration & dosage
- Occlusive Dressings
- Surgical Wound Infection/prevention & control
- Wound Healing